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Search suggestions for "98-92-0".

  1. CEBS Data Related to Nicotinamide (98-92-0) https://cebs.niehs.nih.gov/cebs/test_article/98-92-0


42 results found for "98-92-0".

  1. Mechanistic and Other Relevant Data; Amy Wang; RoC; Jan. 24,... 1.5MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/presentations/mechanistic_508.pdf

    FAD: riboflavin. GSSG: oxidized glutathione. NADPH: reduced from of nicotinamide adenine dinucleotide phosphate. NADP+: nicotinamide adenine dinucleotide phosphate. Antimony ...

  2. National Institute of Environmental Health Sciences: AIDS-01 149KB

    https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/aids-reports/aids-01

    AIDS-01 Full Report (888KB) Abstract Pyrazinamide is a synthetic pyrazine analogue of nicotinamide used in the treatment of tuberculosis, which is an opportunistic infection in the ...

  3. Presentation: Mechanisms of Acute Toxicity 2.4MB

    https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session4/1-wilson-508.pdf

    ... Nicotinamide Adenine Dinucleotide (NADH): a cofactor; reducing potential converted to ATP through the electron transport chain . Nicotinamide adenine dinucleotide phosphate (NADPH) ...

  4. 15th RoC: Acronyms 58KB

    https://ntp.niehs.nih.gov/ntp/roc/content/acronyms_508.pdf

    ... Committee for Acute Exposure Guideline Levels for Hazardous Substances NADPH nicotinamide adenine dinucleotide phosphate, reduced form NAICS North American Industrial ...

  5. Acronyms & Abbreviations 80KB

    https://ntp.niehs.nih.gov/support/acronyms

    ... Committee for Acute Exposure Guideline Levels for Hazardous Substances NADPH Nicotinamide adenine dinucleotide phosphate, reduced form NAICS North American Industrial ...

  6. Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-ruiz-508.pdf

    ... KLF4 Kruppel like factor 4 monitoring protein transport through the cell 18 NAMPT nicotinamide phosphoribosyltransferase epidermal barrier function 19 OTX1 orthodenticle homeobox ...

  7. CERHR Monograph: Potential Human Reproductive and Developmental... 4.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/egpg/ethylene/eg_monograph.pdf

    ... mw molecular weight n or no. number NA not analyzed II-vi NAD nicotinamide adenine dinucleotide NADPH nicotinamide adenine dinucleotide phosphate (reduced) NaHCO 3 sodium ...

  8. TR-048: Pyrazinamide (CASRN 98-96-4) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr048.pdf

    ... Pyrazinamide (pyrazinecarboxamide; CAS 98-96-4; NCI C01785) is a tuberculostatic agent which differs from nicotinamide by the replacement of the pyridine ring with a pyrazine ring. ...

  9. TOX-16: Glyphosate (CASRN 1071-83-6) 1.9MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox016.pdf

    ... inhibition of the energy-linked nicotinamide nucleotide transhydrogenase reaction ... New York: Academic Press, pp. 142- 154. Olorunsogo, O.O. (1982a) Defective nicotinamide ...

  10. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 7.74 3.66 Thiourea 62-56-6 6.41 5.49 2-Butoxyethanol 111-76-2 5.43 8.73 Nicotinamide 98-92-0 5.36 5.78 Glutamic acid 56-86-0 4.84 2.01 Lactic acid 598-82-3 4.16 1.56 Pyridine ...

  11. Background Document: RoC: Captafol; 2010 1.1MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/captafol_final_508.pdf

    ... LD 50 : lethal dose for 50% of the population MNU: N-methyl-N-nitrosourea NADH: nicotinamide adenine dinucleotide NIEHS: National Institute of Environmental Health Sciences ...

  12. Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf

    ... mRNA messenger ribonucleic acid NADPH nicotinamide adenine dinucleotide phosphate ... microsome isolation reagents, and nicotinamide adenine dinucleotide phosphate ...

  13. CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB

    https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf

    ... mmol millimole MS mass spectroscopy mw molecular weight n, no., # number NAD nicotinamide adenine dinucleotide NZW New Zealand White ng nanogram NIEHS National Institute of ...

  14. Background Document: Styrene oxide; BSC RoC, Jan. 20-21, 2000 267KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bg_styrene_oxide_508.pdf

    ... Sample matrix Sample preparations Assay procedure a Limit of detection Reference Rat-liver homogenate react with nicotinamide, incubate fluorimetry 24 - 60 ng Nelis and Sinsheimer ...

  15. Background Document: RoC: o-Nitrotoluene ; 2010 1.5MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/o-nt-final_508.pdf

    ... m 3 : cubic meter mg: milligram mL: milliliter mol wt: molecular weight NADPH: nicotinamide adenine dinucleotide phosphate NCEs: normochromatic erythrocytes NCI National ...

  16. TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf

    ... blocking the oxidation of the reduced nicotinamide adenine dinucleotide (NADH) (Lindahl ... C253. 19. Feinberg, R.; Turrki, P.; Witkowski, P. (1967) The effect of nicotinamide ...

  17. TR-522: Transplacental AZT (CASRN 30516-87-1) in Swiss (CD-1... 5.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr522.pdf

    ... In microsomes pre- pared from human liver, the rate of AMT formation is proportional to cytochrome P450 content and it is enhanced up to fivefold by the addition of nicotinamide- ...

  18. TOX-83: Toxicity Studies of o-Chloropyridine (CASRN 109-09-1... 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox83_508.pdf

    ... Concurrent administration of methionine had a protective effect against toxicity, while cysteine and nicotinamide enhanced the toxicity of o-chloropyridine. In rabbits, ...

  19. Background Document: RoC: Aristolochic Acids ; 2010 2.7MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/aristolochic_acids_final_508.pdf

    ... bromide N: sample size NA: not available N/A: not applicable NADPH: nicotinamide adenine dinucleotide phosphate, reduced form NAG: N-acetyl-β-glucosaminidase ND: ...

  20. DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart07_508.pdf

    ... The parent compound was detected only in feces, accounting for 25%-37% of the administered radioactivity. 12 In liver microsomes, in the presence of nicotinamide adenine ...

  21. GMM-09: Genetically Modified Model Report on Dicyclohexylcarbodiimide... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm09_508.pdf

    ... of the adrenal medulla); Ca 2+ -ATPase of sar- coplasmic reticulum; mitochondrial nicotinamide nucleotide transhydrogenase; cytochrome c oxidase (the terminal ...

  22. Background Document: RoC: Styrene; 2010 4.3MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/styrene_final_508.pdf

    ... available NA-AAF: N-acetoxy-2-acetylaminofluorene NAcT: N-acetyltransferase NADPH: nicotinamide adenine dinucleotide phosphate, reduced form NAP: not applicable NCEs: ...

  23. Background Document: 2,3-Dibromo-1-propanol; BSC; May 24, 2000 824KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/dbp_no_appendices_508.pdf

    ... John et al. 1976, cited in IARC 1979). In vitro, DBP is formed following addition of reduced nicotinamide adenine dinucleotide-dependent microsomal enzymes from rat liver to ...

  24. Final RoC Background Document for Formaldehyde 5.8MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/november/formaldehyde_bd_final.pdf

    ... available NA-AAF: N-acetoxy-2-acetylaminofluorene NAcT: N-acetyltransferase NADPH: nicotinamide adenine dinucleotide phosphate, reduced form NALT: nasal associated lymph tissue ...

  25. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox99_508.pdf

    ... (0.5 μmol), microsomal protein (0.05 mg), testosterone (125 nmol) NADPH = reduced nicotinamide adenine dinucleotide phosphate. a Activity measured as described by BD Biosciences ...

  26. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox99_508.pdf

    ... (0.5 μmol), microsomal protein (0.05 mg), testosterone (125 nmol) NADPH = reduced nicotinamide adenine dinucleotide phosphate. a Activity measured as described by BD Biosciences ...

  27. RoC Background Document: Methyl tertiary-Butyl Ether; Dec. 2... 1.2MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/mtbe1_508.pdf

    ... was shown to be nicotinamide adenine dinucleotive phosphate (NADPH) dependent and inhibitable by carbon monoxide; observations consistent with a role for cytochrome P-450 enzymes. ...

  28. TR-563: Pulegone (CASRN 89-82-7) in F344/N Rats and B6C3F1 Mice... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr563.pdf

    ... For measurement of total glutathione, the supernatant was diluted with 0.2 M phosphate-6.3 mM EDTA buffer and pipetted into a microtiter plate well. Two mM β-nicotinamide adenine ...

  29. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... ferrate II 13943-58-3 15582.05 42.3 6409.6 17.4 5009.8 13.6 368.37 17.4 336 Nicotinamide 98-92-0 5423.02 44.4 3505.4 28.7 NA NA 122.14 28.7 337 Pyridine 110-86-1 3710.26 46.9 ...

  30. TOX-50: Cyclohexanone Oxime 2.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox050.pdf

    ... Unlabeled CHOX was recrystallized from hexane before use. NADPH, NADP, nicotinamide. ... 0.5 ~tmol of NADP, 100 ~tmol of nicotinamide, 25 ~tmol of glucose 6-phosphate, 75 ...

  31. RoC Background Document: Ultraviolet (UV) Radiation, Broad Spectrum... 3.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/uv_no_appendices_508.pdf

    ... porphyrins, quinones, and reduced nicotinamide cofactors (Griffiths et al. 1998). ... quinones, tryptophan, and reduced nicotinamide cofactors (NADH and NADPH) (Ito and ...

  32. TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf

    ... Cancer Inst. 63:849-854. 102. Windmueller, H.; Kaplan, N. (1962) The preparation and properties of Af-hydroxyethyl derivatives of adenosine, adenosine triphosphate and nicotinamide ...

  33. RoC Monograph: 1-Bromopropane; September 2013 1.9MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/1bromopropane_508.pdf

    ... Karmen unit: A formerly used enzyme unit for aminotransferase activity; a change of 0.001 in the absorbance of reduced nicotinamide adenine dinucleotide (NADH) per minute. ...

  34. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    ... Expert Panel Report ABBREVIATIONS Final CERHR Expert Panel Report on Soy Infant Formula II-xxi NADPH nicotinamide adenine dinucleotide phosphate NCI National Cancer Institute NICHD ...

  35. CERHR Monograph: Potential Human Reproductive and Developmental... 5.0MB

    https://ntp.niehs.nih.gov/ntp/ohat/methanol/methanol_monograph.pdf

    ... acid; 2) 4 mg folic acid and vitamins A, D, B 1 , B 2 , B 6 , C, and nicotinamide; 3) vitamins only; or 4) no folic acid or vitamins (ferrous sulfate/di-calcium phosphate control). ...

  36. Background Document: RoC: Riddelliine; 2010 1.7MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/riddelliine_final_508.pdf

    ... R. 1975. Pancreatic islet-cell and other tumors in rats given heliotrine, a monoester pyrrolizidine alkaloid, and nicotinamide. Cancer Res 35(8): 2020-4. (Support not reported. ...

  37. RR-16: Scoping Review of Paraquat Dichloride Exposure and Parkinson... 2.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr16_508.pdf

    ... PLoS One. 7(11):e50683. https://doi.org/10.1371/journal.pone.0050683 Lopert P, Patel M. 2014. Nicotinamide nucleotide transhydrogenase (Nnt) links the substrate requirement in ...

  38. TR-438: Benzethonium Chloride (CASRN 121-54-0) in F344/N Rats... 10.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr438.pdf

    ... Nicotinamide was used as a reference standard. Plates were examined under shortwave (254 nm) ultraviolet light and a spray of iodoplatinate reagent. . HPLC was performed using a ...

  39. Background Document for Selected Heterocyclic Amines: PhIP, MeIQ... 3.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcaspub_508.pdf

    ... Formation of 8- oxodG, by MeIQx(NHOH) in the presence of Cu(II), and β-nicotinamide adenine dinucleotide (NADH), was measured in calf thymus DNA. MeIQx(NHOH) induced DNA damage in ...

  40. TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf

    ... (disodium salt) (ATP), glucose-6-phosphate, glucose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate (NADP + ), nuclease P1, micrococcal nuclease (MN), ...

  41. TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf

    ... 1) ch1oroform:methanol:concentrated ammonium hydroxide . (9550.5) and 2) n-butano1:water:glacial acetic acid (6617:17). Nicotinamide was used as a reference standard. ...

  42. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... 119.37 13.4 1599.6 7.61 908.4 Benzoic acid 122.13 15.7 1917.4 20.7 2528.1 Nicotinamide 122.14 44.4 5423.0 28.7 3505.4 K-26 In Vitro Cytotoxicity Test Methods BRD Appendix ...

 
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