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CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/bisphenol/bisphenol.pdf
MoNogRaPH oN THE PoTENTial HuMaN REPRoduCTivE aNd dEvEloPMENTal EffECTs of BisPHENol a ... at current human expo- sures to bisphenol A. The NTP has minimal concern for ...
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RR-09: The CLARITY-BPA Core Study: A Perinatal and Chronic Extended... 5.1MB
https://ntp.niehs.nih.gov/go/rr09
NTP ReseaRch RePoRT oN The cLaRITY-BPa coRe sTudY: a PeRINaTaL aNd chRoNIc exTeNded-dose- RaNge sTudY of BIsPheNoL a IN RaTs NTP RR 9 SEPTEMBER 2018 NTP Research Report on the ...
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RR-04: Biological Activity of Bisphenol A (BPA) Structural Analogues... 7.7MB
https://ntp.niehs.nih.gov/go/rr04
Biological acTiviTy of BisPheNol a (BPa) sTRucTuRal aNalogues aNd fuNcTioNal alTeRNaTives NTP RR 4 OCTOBER 2017 NTP Research Report on Biological Activity of Bisphenol A (BPA) ...
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TR-215: Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1Mice... 4.3MB
https://ntp.niehs.nih.gov/go/tr215
OFFICIAL NTP FILE COPY THIS OFFICE J I B 0 U W I & ^FMI I W « No. 215 . CARCINOGENESIS BIOASSAY OF BISPHENOL A (CAS NO. 80-05-7) IN F344 RATS AND B6C3F 1 MICE (FEED STUDY) U.S. ...
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CLARITY-BPA Program 69KB
https://ntp.niehs.nih.gov/research/topics/bpa
bpa CLARITY-BPA Program The CLARITY-BPA Core Study Research Report, CLARITY-BPA Grantee Studies data, and CLARITY-BPA Compendium Report are now available. Various sizes of metal ...
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Abstract for RR-09 128KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr09
9abs Abstract for RR-09 The CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats CASRN: 80-05-7 Chemical Formula: C15-H16-O2 Synonyms/...
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Peer Review Report: Draft NTP Research Report on the CLARITY... 557KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/rrprp/2018/april/peerreview_20180426_508.pdf
Draft NTP Research Report on the CLARITY-BPA Core Study April 26, 2018 National ... Draft NTP Research Report on the CLARITY-BPA Core Study 2 Table of Contents I. Attendees ...
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Bisphenol A: Target Organs and Levels of Evidence for TR-215 50KB
https://ntp.niehs.nih.gov/data/tr/200s/tr215levels
2 Bisphenol A: Target Organs and Levels of Evidence for TR-215 Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study) Chemical (Study ...
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RR-09: Lay Summary; Bisphenol A (CASRN 80-05-7) 221KB
https://ntp.niehs.nih.gov/sites/default/files/2024-08/rr09_summary_508.pdf
CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats RR-09 Full report: https://ntp.niehs.nih.gov/go/rr09abs SUMMARY Background: ...
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2018 CLARITY-BPA Preliminary Agenda 184KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/rrprp/2018/april/agenda20180426_508.pdf
Agenda Peer Review Meeting of Draft NTP Research Report on the CLARITY-BPA Core Study ... Dorman Presentation on the Overall CLARITY-BPA Program Dr. Nigel Walker, NIEHS/DNTP Peer ...
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Abstract for RACB82081 53KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb82081
Abstract for RACB82081 Bisphenol A: Reproduction and Fertility Assessment in CD-1 Mice When Administered Via Subcutaneous Silastic® Implants CASRN: 80-05-7 Chemical Formula: ...
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Abstract for TER85052 53KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter85052
Abstract for TER85052 Teratologic Evaluation of Bisphenol A Administered to CD-1 Mice on Gestational Days 6 Through 15 CASRN: 80-05-7 Chemical Formula: C15H16O2 Molecular Weight: ...
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Abstract for TER85051 53KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter85051
Abstract for TER85051 Teratologic Evaluation of Bisphenol A Administered to CD Rats on Gestational Days 6 Through 15 CASRN: 80-05-7 Chemical Formula: C15H16O2 Molecular Weight: ...
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Abstract for RACB84080 55KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84080
80abs Abstract for RACB84080 Bisphenol A: Reproduction and Fertility Assessment in CD-1 Mice When Administered in the Feed CASRN: 80-05-7 Chemical Formula: C15H16O2 Molecular ...
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Endocrine Disruptors Low-Dose Peer Review, October 10-12, 2000 17.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/pressctr/mtgs_wkshps/2000/lowdosepeerfinalrpt.pdf
xvi CHAPTER 1 Report of the Bisphenol A Subpanel ......The Panel was divided into five subpanels: Bisphenol A, Other Environmental Estrogens and ...
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Abstract for RR-18 53KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr18
Abstract for RR-18 Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity (CLARITY-BPA): A Compendium of Published Findings CASRN: 80-05-7 Chemical Formula: ...
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Abstract for RR-04 52KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr04
4abs Abstract for RR-04 Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives Report Date: October 2017 Full Report PDF Abstract Background ...
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Abstract for TR-215 54KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr215
5abs Abstract for TR-215 Carcinogenesis Bioassay of Bisphenol A in F344 Rats and B6C3F1 Mice (Feed Study) CASRN: 80-05-7 Chemical Formula: C15H16O2 Molecular Weight: 228.289 ...
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Using APROBA for Integrated TDI Derivation and Uncertainty Analysis... 1.5MB
https://ntp.niehs.nih.gov/sites/default/files/2025-01/1_2_Herzler_EPAWksp2024_508.pdf
Using APROBA for integrated TDI derivation and uncertainty analysis - the case of BPA ... This presentation is not about the correct TDI for BPA, only about how we derived one ...
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Minutes: BSC; June 20, 2018 348KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/june/minutes20180620_508.pdf
.........21 1) CLARITY-BPA Research Program: Peer Review of Core Study ... Big Data 2 Knowledge BMD benchmark dose BPA bisphenol A BPAF bisphenol AF BPS bisphenol ...
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Research Reports 93KB
https://ntp.niehs.nih.gov/publications/reports/rr
PDF (2.96 MB) Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity (CLARITY-BPA): A Compendium of Published Findings 2021 Research Report RR-17 PDF (960.56 ...
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Minutes: BSC; Dec. 12, 2018 441KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/december/minutesbsc20181212_508.pdf
......... 15 VIII. CLARITY-BPA Research Program: Integration Report ... Counselors 3 I. Abbreviations and Acronyms BPA bisphenol A BSC Board of Scientific ...
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Minutes: BSC; Nov. 30-Dec. 1, 2010 984KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2010/novdec/minutes20101201.pdf
... Health of Men Working with Bisphenol A in the United State ...... 62 ... Registry BDE brominated diphenyl ether BPA bisphenol A BPDP tert-butylphenyl diphenyl ...
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BG1Luc ER TA Protocol Standardization Study Report (Annex C of... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexc/c0-prot-stand.pdf
... C-58 10.2.2 N0002 - Bisphenol A ......C-58 Table 10-5 Concentrations of N0002 - Bisphenol A Used in Comprehensive Testing ...
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Implementation of Non-animal Approaches for Acute Systemic Toxicity 1.6MB
https://ntp.niehs.nih.gov/iccvam/meetings/at-models-2018/ppt/1-patlewicz.pdf
over Prioritization Mode Desc Summary Log 80-05-7 80-05-1 80-05-2 80-05-3 80-05-5 CHEMICAL SUMMARY CASRN Chemical Name 80-05-7 Bisphenol A 80-05-1 Bisphenol B 80-05-2 ...
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Update on Alternatives Research at EPA (ICCVAM Public Forum 2021... 1.8MB
https://ntp.niehs.nih.gov/sites/default/files/iccvam/meetings/iccvam-forum-2021/present/11_thomas-508.pdf
over Prioritization Mode Desc Summary Log 80-05-7 80-05-1 80-05-2 80-05-3 80-05-5 CHEMICAL SUMMARY CASRN Chemical Name 80-05-7 Bisphenol A 80-05-1 Bisphenol B 80-05-2 ...
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Abstract for TR-203 53KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr203
Approximately 90% of the phenol produced is used in the manufacture of phenolic (phenol formaldehyde) resins, caprolactam, bisphenol A, alkyl phenol, and adipic acid. The remainder ...
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Minutes: BSC; June 17-18, 2014 290KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/june/minutes20140618_508.pdf
... absorption, distribution, metabolism, and excretion AOP adverse outcome pathway BPA bisphenol A BPAF bisphenol AF BPS bisphenol S BSC Board of Scientific Counselors CDC Centers ...
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Minutes: BSC; Dec. 11, 2012 248KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2012/december/bscminutes20121211_508.pdf
......... 22 VIII. NTP Update: BPA Studies and a Cooperative (U01) BPA Research Consortium ...... 23 IX. Adjournment ...
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Safe and Sustainable Alternatives Program; Stephen Ferguson;... 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2021/august/presentations/ssa_bsc_presentation_508.pdf
BPA Other bisphenols ? PBB flame retardants PBDE flame retardants OP flame retardants ... BPA analogues more similar to one another than estradiol - ADME-toxicokinetics: similar ...
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Minutes: BSC; Oct. 9, 2018 718KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/october/minutes20181009_508.pdf
AOP adverse outcome pathway BD2K Big Data 2 Knowledge BMD benchmark dose BPA bisphenol A BPAF bisphenol AF BPS bisphenol S BSC Board of Scientific Counselors CDC Centers ...
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Minutes: BSC; June 21-22, 2012 280KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2012/june/bscminutes20120622_508.pdf
... Counselors 1 I. Frequently Used Abbreviations and Acronyms AZT zidovudine BPA bisphenol A BSC Board of Scientific Counselors CDC Center for Disease Control and Prevention ...
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Minutes: BSC; June 15-16, 2016 457KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2016/june/minutes201606_508.pdf
... Abbreviations and Acronyms ADME absorption, distribution, metabolism, excretion BPA bisphenol A BSB Biomolecular Screening Branch BSC Board of Scientific Counselors CDMA Code ...
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Public Health Impact 1.9MB
https://ntp.niehs.nih.gov/media/impact
... A, Holmgren S, Hsieh J-H, Svoboda D, Auerbach S et al. 2017. NTP research report on biological activity of bisphenol A (BPA) structural analogues and functional alternatives. ...
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Completed Evaluations 70KB
https://ntp.niehs.nih.gov/research/assessments/noncancer/completed
Go » photo of inside of can and paper receipt Bisphenol A Structural Analogues Scoping review of the biological activity of BPA analogues. Go » Pregnant woman with Cancer ...
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Minutes: BSC; December 14-15, 2016 348KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2016/december/minutes20161214_508.pdf
... NTP Board of Scientific Counselors 2 I. Frequently Used Abbreviations and Acronyms BPA bisphenol A BSC Board of Scientific Counselors CDC Centers for Disease Control and ...
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Minutes: BSC; June 16, 2015 579KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2015/june/bsc_jun2015_minutes_508-.pdf
... Council ATSDR Agency for Toxic Substances and Disease Registry BMD benchmark dose BPA bisphenol A BSC Board of Scientific Counselors CDC Centers for Disease Control and ...
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NTP Report on Endocrine Disruptors Low-Dose Peer Review 60KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/pressctr/mtgs_wkshps/2000/lowdoseprogram.pdf
Endocrine Disruptors Low-Dose Peer Review - SubPanels Bisphenol A Chair: George Stancel, ... 8:00 PM Subpanels: Initial Meeting 1. Bisphenol A 2. Other Environmental Estrogens and ...
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Agency Response to ICCVAM Recommendations on In Vitro Cytotoxicity... 271KB
https://ntp.niehs.nih.gov/iccvam/methods/acutetox/agencyresp/epa_resp.pdf
Specifically, ICCVAM seeks to know ifthe . Envi.Ionmentat Protection AgenCy (BPA) wlll ... BPA was iDstriuncntal in ha'Ving ICCVAM review the revised UDP and this review was ...
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Expanding PBPK Modeling to Predict Chemical Distribution in Brain... 1.8MB
https://ntp.niehs.nih.gov/sites/default/files/2023-09/Unnikrishnan-WC12-poster-FD.pdf
... We chose bisphenol A as the test chemical for the adipose compartment. Bisphenol A is a lipophilic chemical that accumulates in human tissues, which can contribute to development ...
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Site Map 55KB
https://ntp.niehs.nih.gov/support/sitemap
Artificial Butter Flavorings (ABF) Components Botanical Dietary Supplements Cell Phones CLARITY-BPA Glyphosate & Glyphosate Formulations Hexavalent Chromium Mold Polyfluorinated ...
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Agenda: NTP Workshop: Role of Environmental Chemicals in the... 149KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/diabetesobesity/finalagenda1_19_2011klh.pdf
meetings · Arsenic and other metals · BPA · Organotins and phthalates · Nicotine · ... Boekelheide, Brown University 9:00 BPA, other steroid hormones and thyroid hormones - Dr. ...
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Agenda: Webinar on Lessons Learned in Application of the OHAT... 78KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/evaluationprocess/agendawebinar20140731_508.pdf
for two case studies, BPA and obesity and PFOA/PFOS and immunotoxicity, which the Office of Health Assessment and Translation (OHAT) planned to undertake using the OHAT approach. ...
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Peer Review Panel Report on Evaluation of the LUMI-CELL ER Test... 287KB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edprprept2011.pdf
... Abbreviations and Acronyms BG1Luc ER TA LUMI-CELL ® BG-1Luc4E2 ER TA test method BPA Bisphenol A BRD Background review document CERI Chemicals Evaluation and Research Institute ...
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Applying In vitro Approaches to Understand Complex Mixtures in... 5.3MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-rider-508.pdf
EPA (2000) Supplementary Guidance for Problem formulation Adapted from U.S Conducting Health Risk Assessment of Chemical Mixtures Bisphenol A & Analogues Botanical Dietary ...
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Minutes: BSC; June 29, 2017 285KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2017/june/minutes20170629_508.pdf
Toxic Substances and Disease Registry AUC area under the curve BMD benchmark dose BPA bisphenol A BSC Board of Scientific Counselors CDC Centers for Disease Control and ...
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Agenda: Workshop on Probabilistic Methods for Health Assessments... 33KB
https://ntp.niehs.nih.gov/sites/default/files/2024-10/AbridgedAgenda_ProbWorkshop_FINAL_rev_508.pdf
AM Using APROBA for integrated TDI derivation and uncertainty analysis - the case of BPA Matthias Herzler (BfR) 9:50 - 10:10 AM APROBA case study application in EPA human health ...
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Abstract for DART-08 118KB
https://ntp.niehs.nih.gov/publications/reports/dart/dart08
BPAF was selected for evaluation based on a review of compounds that are potentially endocrine-active after concerns were raised about possible effects of bisphenol A (BPA) on the ...
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Agenda: BSC; June 20, 2018 423KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/june/agenda20180620_508.pdf
LUNCH 2: 00 . Activities on Bisphenols - CLARITY-BPA Research Program: Peer Review of Core Study and Next Steps* o Public Comments o BSC Discussion - Evaluation of Bisphenol ...
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DART-08: Lay Summary; Bisphenol AF (CASRN 1478-61-1) 193KB
https://ntp.niehs.nih.gov/sites/default/files/2025-03/dart08_summary_508.pdf
BPAF was selected for evaluation due to concerns about the potential health effects of a related chemical, bisphenol A (BPA), in fetuses, infants, and children. The effects of BPAF ...
