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211 results found for "Bisphenol A".
  1. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/bisphenol/bisphenol.pdf

    MoNogRaPH oN THE PoTENTial HuMaN REPRoduCTivE aNd dEvEloPMENTal EffECTs of BisPHENol a ... NTP.Brief.on.Bisphenol.A......

  2. DART-08: Modified One-Generation Study of Bisphenol AF (CASRN... 5.8MB

    https://ntp.niehs.nih.gov/go/dart08

    moDifieD oNe-GeNeRaT ioN STuDy of BiSPheNol af (caSRN 1478-61-1) aDmiNiSTeReD iN feeD To ... on the Modified One-Generation Study of Bisphenol AF (CASRN 1478-61-1) Administered in ...

  3. TR-215: Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1Mice... 4.3MB

    https://ntp.niehs.nih.gov/go/tr215

    « No. 215 . CARCINOGENESIS BIOASSAY OF BISPHENOL A (CAS NO. 80-05-7) IN F344 RATS AND ... on the CARCINOGENESIS BIOASSAY of BISPHENOL A (CAS NO. 80-05-7) IN F344 RATS AND ...

  4. RR-04: Biological Activity of Bisphenol A (BPA) Structural Analogues... 7.7MB

    https://ntp.niehs.nih.gov/go/rr04

    Biological acTiviTy of BisPheNol a (BPa) sTRucTuRal aNalogues aNd fuNcTioNal alTeRNaTives NTP RR 4 OCTOBER 2017 NTP Research Report on Biological Activity of Bisphenol A (BPA) ...

  5. Bisphenol A: Target Organs and Levels of Evidence for TR-215 51KB

    https://ntp.niehs.nih.gov/data/tr/200s/tr215levels

    2 Bisphenol A: Target Organs and Levels of Evidence for TR-215 Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study) Chemical (Study ...

  6. RR-09: The CLARITY-BPA Core Study: A Perinatal and Chronic Extended... 5.1MB

    https://ntp.niehs.nih.gov/go/rr09

    sTudY of BIsPheNoL a IN RaTs NTP RR 9 SEPTEMBER 2018 NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats ...

  7. Abstract for RACB84080 56KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84080

    80abs Abstract for RACB84080 Bisphenol A: Reproduction and Fertility Assessment in CD-1 ... Bisphenol A (BPA), used in the manufacture of epoxy resins and polycarbonates, was tested ...

  8. Abstract for DART-08 119KB

    https://ntp.niehs.nih.gov/publications/reports/dart/dart08

    Abstract for DART-08 Modified One-Generation Study of Bisphenol AF Administered in Feed to ... Full Report PDF Lay Summary Abstract Bisphenol AF (BPAF) is used as a curing or ...

  9. Abstract for RR-09 129KB

    https://ntp.niehs.nih.gov/publications/reports/rr/rr09

    Study of Bisphenol A in Rats CASRN: 80-05-7 Chemical Formula: C15-H16-O2 Synonyms/Common Names: BPA; 4,4'-(1-Methylethylidene)bisphenol Report Date: September ...

  10. DART-08: Lay Summary; Bisphenol AF (CASRN 1478-61-1) 193KB

    https://ntp.niehs.nih.gov/sites/default/files/2025-03/dart08_summary_508.pdf

    the Modified One- Generation Study of Bisphenol AF (CASRN 1478-61-1) Administered in .../go/dart08abs SUMMARY Background: Bisphenol AF (BPAF) is a chemical used in the ...

  11. Abstract for TER85051 54KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter85051

    Abstract for TER85051 Teratologic Evaluation of Bisphenol A Administered to CD Rats on ... Bisphenol A, a widely distributed industrial chemical used in making epoxy resins and ...

  12. Abstract for TER85052 54KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter85052

    Abstract for TER85052 Teratologic Evaluation of Bisphenol A Administered to CD-1 Mice on ... Bisphenol A, a widely distributed industrial chemical used in making epoxy resins and ...

  13. Abstract for RACB82081 54KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb82081

    1abs Abstract for RACB82081 Bisphenol A: Reproduction and Fertility Assessment in CD-1 ... Bisphenol A (BPA) was examined in the Reproductive Assessment by Continuous Breeding ...

  14. RR-09: Lay Summary; Bisphenol A (CASRN 80-05-7) 221KB

    https://ntp.niehs.nih.gov/sites/default/files/2024-08/rr09_summary_508.pdf

    Chronic Extended-Dose-Range Study of Bisphenol A in Rats RR-09 Full report: https://ntp.niehs.nih.gov/go/rr09abs SUMMARY Background: Bisphenol A (BPA) is an industrial chemical ...

  15. Abstract for TR-215 55KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr215

    Abstract for TR-215 Carcinogenesis Bioassay of Bisphenol A in F344 Rats and B6C3F1 Mice ... Full Report PDF Abstract A carcinogenesis bioassay of bisphenol A, an intermediate used in ...

  16. Abstract for RR-18 55KB

    https://ntp.niehs.nih.gov/publications/reports/rr/rr18

    Bisphenol A Toxicity (CLARITY-BPA): A Compendium of Published Findings CASRN: 80-05-7 Chemical Formula: C15-H16-O2 Synonyms/Common Names: BPA; 4,4'-(1-methylethylidene)bisphenol ...

  17. BG1Luc ER TA Protocol Standardization Study Report (Annex C of... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexc/c0-prot-stand.pdf

    ... N0002 - Bisphenol A ...... C-61 ICCVAM BG1Luc ER TA Evaluation Report C-4 10.2.3 N0003 - Bisphenol B ...

  18. Abstract for TR-40 54KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr040

    Full Report PDF Abstract Hexachlorophene is a chlorinated bisphenol which was widely used as an antiseptic prior to 1972. It is highly effective against gram-positive bacteria and ...

  19. Abstract for RR-04 53KB

    https://ntp.niehs.nih.gov/publications/reports/rr/rr04

    Abstract for RR-04 Biological Activity of Bisphenol A (BPA) Structural Analogues and ... functional similarity to bisphenol A (BPA), referred to as BPA analogues or derivatives. ...

  20. CLARITY-BPA Program 71KB

    https://ntp.niehs.nih.gov/research/topics/bpa

    Various sizes of metal food container cans Research Overview Status: Completed Substances: Bisphenol A Background Information Bisphenol A (BPA) is a chemical produced in large ...

  21. Update on Alternatives Research at EPA (ICCVAM Public Forum 2021... 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/iccvam/meetings/iccvam-forum-2021/present/11_thomas-508.pdf

    Desc Summary Log 80-05-7 80-05-1 80-05-2 80-05-3 80-05-5 CHEMICAL SUMMARY CASRN Chemical Name 80-05-7 Bisphenol A 80-05-1 Bisphenol B 80-05-2 Bisphenol C 80-05-3 Bisphenol D ...

  22. Research Reports 94KB

    https://ntp.niehs.nih.gov/publications/reports/rr

    Academic and Regulatory Insights on Bisphenol A Toxicity (CLARITY-BPA): A Compendium ... Chronic Extended-Dose-Range Study of Bisphenol A in Rats 2018 Research Report RR-08 PDF ...

  23. Abstract for TR-203 55KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr203

    Approximately 90% of the phenol produced is used in the manufacture of phenolic (phenol formaldehyde) resins, caprolactam, bisphenol A, alkyl phenol, and adipic acid. The remainder ...

  24. RoC Protocol: Organohalogen Flame Retardants; Jan. 31, 2025 662KB

    https://ntp.niehs.nih.gov/sites/default/files/2025-03/organohalogen_flame_retardants_508.pdf

    ... IARC Classification Polyhalogenated bisphenol aliphatics and functionalized (PBAFs) ... RoC, we identified the following NAS- defined OFR subclasses: 1. Polyhalogenated bisphenol ...

  25. Public Health Impact 1.9MB

    https://ntp.niehs.nih.gov/media/impact

    ... At this meeting the DARTIC will consider the possible listing of bisphenol S (BPS) based ... identification document entitled "Evidence on the Developmental Toxicity of Bisphenol S". ...

  26. Expanding PBPK Modeling to Predict Chemical Distribution in Brain... 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-09/Unnikrishnan-WC12-poster-FD.pdf

    ... We chose bisphenol A as the test chemical for the adipose compartment. Bisphenol A is a lipophilic chemical that accumulates in human tissues, which can contribute to development ...

  27. Completed Evaluations 71KB

    https://ntp.niehs.nih.gov/research/assessments/noncancer/completed

    Go » photo of inside of can and paper receipt Bisphenol A Structural Analogues Scoping review of the biological activity of BPA analogues. Go » Pregnant woman with Cancer ...

  28. Applying In vitro Approaches to Understand Complex Mixtures in... 5.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-rider-508.pdf

    EPA (2000) Supplementary Guidance for Problem formulation Adapted from U.S Conducting Health Risk Assessment of Chemical Mixtures Bisphenol A & Analogues Botanical Dietary ...

  29. Reproductive Abstracts 197KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro

    ... CD-1 Mice When Administered in the Drinking Water 1984 Reproductive RACB82081 Bisphenol A Bisphenol A: (CASRN: 80-05-7) Reproduction and Fertility Assessment in CD-1 Mice When ...

  30. Comment: National Toxicology Program Board of Scientific Counselors... 328KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/kall20230428_bsc_508.pdf

    We have especially focused on three commonly used toxic materials in dentistry: 1. mercury, a neurotoxin, used in amalgam fillings 2. bisphenol A, an endocrine disrupter, used in ...

  31. Minutes: BSC; June 29, 2017 285KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2017/june/minutes20170629_508.pdf

    Substances and Disease Registry AUC area under the curve BMD benchmark dose BPA bisphenol A BSC Board of Scientific Counselors CDC Centers for Disease Control and Prevention ...

  32. Peer Review Panel Report on Evaluation of the LUMI-CELL ER Test... 287KB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edprprept2011.pdf

    ... ® BG-1Luc4E2 ER TA test method BPA Bisphenol A BRD Background review document CERI ... Peer Review Panel Report 24 and bisphenol-A may deserve to be an ED by many ...

  33. ICE Tools to Facilitate PBPK Modeling and IVIVE for Various Exposure... 1016KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ascct-2022/unnikrishnan_ascct-2022-poster_fd.pdf

    ... Bisphenol A The box-and-whisker plots show distribution of Cmax values for all query ... Oral route of exposure 17-Methyltestosterone Bisphenol A 17-beta-Estradiol ...

  34. Using APROBA for Integrated TDI Derivation and Uncertainty Analysis... 1.5MB

    https://ntp.niehs.nih.gov/sites/default/files/2025-01/1_2_Herzler_EPAWksp2024_508.pdf

    Disclaimers Background - recent work on Bisphenol A (BPA) 12/21: EFSA draft opinion on ... Bisphenol A Methodology used to develop BfR opinion Dr. Matthias Herzler | Advancing ...

  35. Minutes: BSC; June 15-16, 2016 457KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2016/june/minutes201606_508.pdf

    ... distribution, metabolism, excretion BPA bisphenol A BSB Biomolecular Screening Branch BSC ... Birnbaum noted recent Congressional briefings on endometriosis awareness and bisphenol A ...

  36. Developmental Neurotoxicity Screening Assay Chemical List | National... 418KB

    https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/health/developmental/chemical-list

    ... Mixture* 107534-96-3 DTXSID9032113 Tebuconazole Mixture* 80-05-7 DTXSID7020182 Bisphenol A ... Mixture* NOCAS_ 1354862 DTXSID801354862 Bisphenol A + Acrylamide (1:10 molarity (Bisphenol ...

  37. PBPK Modeling to Predict Chemical Distribution in Brain and Adipose... 1.4MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Unnikrishnan-poster.pdf

    ... Adipose Acetaminophen 6.1 4.2 1 2.5 Bisphenol A 7.4 2.7 1.5 12 Cmax* - Maximum ... diazepam, trichloroethylene, deltamethrin, acetaminophen, bisphenol A and dieldrin. . ...

  38. FAQs & Fact Sheets 62KB

    https://ntp.niehs.nih.gov/media/faqs

    to Animal Testing FAQ Dec 2025 Arsenic FAQ Dec 2025 Autoimmune Diseases FAQ Dec 2025 Bisphenol A (BPA) FAQ Dec 2025 Breast Cancer FAQ Dec 2025 Cell Phone Radiofrequency Radiation ...

  39. Study Abstracts 370KB

    https://ntp.niehs.nih.gov/publications/abstracts

    ... CD-1 Mice When Administered in the Drinking Water 1984 Reproductive RACB82081 Bisphenol A Bisphenol A: (CASRN: 80-05-7) Reproduction and Fertility Assessment in CD-1 Mice When ...

  40. Synthetic Turf/Recycled Tire Crumb Rubber 62KB

    https://ntp.niehs.nih.gov/research/topics/syntheticturf

    although they did confirm that it contains many substances, such as polycyclic aromatic hydrocarbons (PAHs), metals, plasticizers, such as phthalates, and bisphenol A (BPA). ...

  41. ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf

    ... (3/3) Bicalutamide 90357-06-5 NEG NEG NEG (1/1) NT NT Bisphenol A 80-05-7 POS POS POS (3/3) POS (3/3) POS (3/3) Bisphenol B 77-40-7 POS POS POS (3/3) POS (3/3) POS (3/3) ...

  42. Minutes: BSC; Dec. 11, 2012 248KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2012/december/bscminutes20121211_508.pdf

    ... and Acronyms ADME absorption, distribution, metabolism and elimination BPA bisphenol A BSC Board of Scientific Counselors DNTP Division of the NTP EPA U.S. Environmental ...

  43. Acronyms & Abbreviations 76KB

    https://ntp.niehs.nih.gov/support/acronyms

    neoplasia CLARITY-BPA Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity CoCrMo Cobalt-chromium-molybdenum COX Cyclooxygenase CPSC Consumer Product ...

  44. Highlighted Research Topics 65KB

    https://ntp.niehs.nih.gov/research/topics

    CLARITY-BPA CLARITY-BPA is studying a range of potential health effects from exposure to bisphenol A. The program unites standard regulatory research practices with innovative ...

  45. Join the Expert Directory 124KB

    https://ntp.niehs.nih.gov/getinvolved/expert_directory_form

    ... - Asbestos/Mineral fibers Exposure - Bisphenol A Exposure - Botanicals/herbals Exposure ... - Asbestos/Mineral fibers Exposure - Bisphenol A Exposure - Botanicals/herbals Exposure ...

  46. RoC Profile: 4-Vinyl-1-cyclohexene Diepoxide; 15th RoC 2021 127KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/vinylcyclohexenediepoxide.pdf

    Use 4-Vinyl-1-cyclohexene diepoxide is used as a reactive diluent for other diepoxides and for certain epoxy resins derived from bisphenol A and epichlorohydrin (NTP 1989). The ...

  47. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER ... (DES) (1.23 x 10 -5 mg/ml); Bisphenol A (7.81 x 10 -2 25 mg/ml); Estrone (7.81 ...

  48. NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf

    ... 2 Atrazine POS (3/3) NEG (3/3) POS (1/1) NT POS NEG 2 Bisphenol A POS (3/3) POS (3/3) POS (1/1) POS (1/1) POS POS 2 Bisphenol B POS (3/3) POS (3/3) POS (1/1) POS (1/1) POS POS 2 ...

  49. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER ... (DES) (1.23 x 10 -5 mg/ml); Bisphenol A (7.81 x 10 -2 25 mg/ml); Estrone (7.81 ...

  50. Monographs 65KB

    https://ntp.niehs.nih.gov/publications/monographs

    ... All NTP-CERHR Monographs Substance/Topic Year Acrylamide 2005 Amphetamines 2005 Bisphenol A 2008 1-Bromopropane 2003 2-Bromopropane 2003 Ethylene Glycol 2004 Fluoxetine 2004 ...

 
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