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410 results found for "PCB".
  1. TR-530: Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB... 8.2MB

    https://ntp.niehs.nih.gov/go/tr530

    2',4,4',5,5'- HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN ... OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) AND ...

  2. TR-531: Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB... 7.2MB

    https://ntp.niehs.nih.gov/go/tr531

    3',4,4',5- PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN ... OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) AND ...

  3. RoC Profile: Polychlorinated Biphenyls; 15th RoC 2021 176KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/polychlorinatedbiphenyls.pdf

    Also known as PCBs or chlorodiphenyls (Cl) x (Cl) y Polychlorinated biphenyls (number of chlorine atoms [x + y] = 1-10) Carcinogenicity Polychlorinated biphenyls (PCBs) are ...

  4. TR-529: 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065... 4.0MB

    https://ntp.niehs.nih.gov/go/tr529

    OF 2,2',4,4',5,5' -HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN ... OF 2,2N,4,4N,5,5N-HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN ...

  5. TR-559: 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508... 5.4MB

    https://ntp.niehs.nih.gov/go/tr559

    2,3',4,4',5- PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN ... STUDIES OF 2,3´,4,4´,5-PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE ...

  6. Abstract for TR-530 76KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr530

    Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) in Female Harlan ...

  7. TR-520: 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465... 12.8MB

    https://ntp.niehs.nih.gov/go/tr520

    OF 3,3',4,4',5- PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN ... OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN ...

  8. TR-526: Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD... 6.6MB

    https://ntp.niehs.nih.gov/go/tr526

    AND 3,3',4,4',5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN ... AND 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN ...

  9. Abstract for TR-531 75KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr531

    Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) in Female Harlan Sprague-Dawley ...

  10. TR-525: 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CASRN 57117... 4.3MB

    https://ntp.niehs.nih.gov/go/tr525

    ... structurally related poly- chlorinated biphenyls (PCBs) and mixtures of these compounds. ... polychlorinated dibenzodioxins (PCDDs), polychlori- nated dibenzofurans (PCDFs), and PCBs. ...

  11. Abstract for TR-38 56KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr038

    Aroclor® is the registered trademark of the Monsanto Chemical Company for their polychlorinated biphenyls (PCBs). PCBs were developed in 1929 primarily for use as heat transfer ...

  12. TR-521: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (CASRN 1746... 12.8MB

    https://ntp.niehs.nih.gov/go/tr521

    ... structurally related poly- chlorinated biphenyls (PCBs) and mixtures of these compounds. ... polychlorinated dibenzodioxins (PCDDs), polychlori- nated dibenzofurans (PCDFs), and PCBs. ...

  13. Abstract for TR-529 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr529

    Toxicology and Carcinogenesis Studies of 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) in ... related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...

  14. Abstract for TR-520 69KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr520

    Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) in ... polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...

  15. NTP Monograph on Health Effects of Low-Level Lead Appendix E... 2.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/lead/final/leadappendixe_final_508.pdf

    BMI, and other pollutants (p,p'-DDE, HCB, PCBs, mirex, mercury) Binary Logistic ... µg/dL 12.7 years (12.2-13.1) Increasing PCB levels were associated with a greater ...

  16. Abstract for TR-526 71KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr526

    and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) in Female Harlan Sprague-Dawley Rats ... 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) Report Date: ...

  17. Target Organs and Levels of Evidence for TR-531 54KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr531levels

    Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN ...

  18. Abstract for TR-559 65KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr559

    Toxicology and Carcinogenesis Studies of 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) in ... and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...

  19. Historical Controls: Pathology Tables for All Routes/Vehicles... 81KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2009/2008_hc_report_sd_rats_byroute.pdf

    Battelle Columbus Laboratory 059602001 N/A N/A 0 (0) 0(0) N/A TEF evaluation (Binary mixture; PCB 126/PCB 153) Battelle Columbus Laboratory 059600704 N/A N/A 0 (0) 0(0) N/A TEF ...

  20. Target Organs and Levels of Evidence for TR-530 53KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr530levels

    Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN ...

  21. Target Organs and Levels of Evidence for TR-520 53KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr520levels

    Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN ... Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl) ...

  22. Target Organs and Levels of Evidence for TR-529 51KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr529levels

    Toxicology and Carcinogenesis Studies of 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) ... Toxic equivalency factor evaluation (PCB 153- 2,2'-4,4',5,5'-hexachlorobiphenyl) ...

  23. NTP Monograph on Health Effects of Low-Level Lead Appendix B... 873KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/lead/final/leadappendixb_final_508.pdf

    ... (conA) response, NK function, plasma PCBs, chlorin- ated pesticides, metals ... Correlation for serum IgG and cord blood: Pb level - IgG r=0.31; p=0.002 Sum PCBs - IgG ...

  24. RoC Background Document: 2,3,7,8-Tetrachlorodibenzo-p-dioxin... 7.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/tetrachl_tcdd_4apps_508.pdf

    ... of action ofTCDD and other chlorinated dibenzodioxins, dibenzofurans, and planar PCBs. ... hospital wastes; PCB-filled electrical transformer fires; and smelters (Schecter, 1994). ...

  25. A multi-tiered hierarchical Bayesian approach to derive toxic... 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/2025-01/2d_1_Ring_EPAWksp2024_508.pdf

    Polychlorinated dibenzofurans (PCDFs) . Polychlorinated biphenyls (PCBs) Usually occur as ... General chemical structure of PCBs By D.328 - Own work, CC BY-SA 3.0, https://...

  26. TR-038: Aroclor (CASRN 27323-18-8) 1.9MB

    https://ntp.niehs.nih.gov/go/tr038

    ... Aroclor® (CAS 27323-18-8; NCI C02664) is the registered trademark of the Monsanto Chemical Company for their polychlorinated biphenyls (PCBs). PCBs were developed in 1929 ...

  27. Department of the Interior: Potential Metrics to Track and Encourage... 220KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2022/ppt/06_rattner_508.pdf

    Habitat affected by mining, smelting and manufacturing, oil spills Water, soil, plants, SPMDs, inverts, F&W: metals, PAHs, PCBs in vivo (trend toward sublethal and minimally ...

  28. Abstract for TR-521 71KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr521

    and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ... polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...

  29. Abstract for TR-525 68KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr525

    related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ... polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...

  30. NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/lead/final/appendicesathrue_final_508.pdf

    ... Maternal non-verbal intelligence, breastfeeding status, Hg levels, hemoglobin, PCB-153 ... = 0.8 - 27.1) *sig. correlation with PCB153 Venous blood at testing = 5.4 (5.0) ...

  31. RoC Profile: 2,3,7,8-Tetrachlorodibenzo-p-dioxin; 15th RoC 2021 154KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/tetrachlorodibenzodioxin.pdf

    chlorinated dibenzodioxins, dibenzofurans, and planar polychlorinated biphenyls (PCBs). ... municipal, toxic, and hospital wastes, in PCB-filled electrical transformer fires, in ...

  32. TR-558: 3,3',4,4'-Tetrachloroazobenzene (TCAB) (CASRN 14047-09... 18.9MB

    https://ntp.niehs.nih.gov/go/tr558

    ... greater than those observed following administration of TCDD or PCB 126 (NTP, 2006a,b). ... and B6C3F1 Mice a TCAB b TCDD c,d PeCDF e PCB 126 f Adrenal Gland Adenoma +FR - - +/- FR ...

  33. RoC Profile: Mirex; 15th RoC 2021 138KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/mirex.pdf

    ... Kostyniak PJ, Vena JE. 1999. Comparison of PCB congeners and pesticide levels between ... Cole DC, Ferron LA, Weber JP. 1999. Blood PCB, p,p'-DDE, and mirex levels in Great Lakes ...

  34. TR-244: Polybrominated Biphenyl Mixture (Firemaster FF-1) in... 8.6MB

    https://ntp.niehs.nih.gov/go/tr244

    ... toxicity of PBB was quite similar to that induced by PCB in rats (Kasza et al., 1978). ... aromatic hydrocarbons such as the PCB (Allen and Abrahamson, 1973), the diben- ...

  35. TR-584: Indole-3-Carbinol (CASRN 700-06-1) in F344/N Rats and... 4.1MB

    https://ntp.niehs.nih.gov/go/tr584

    ... the current study of indole-3-carbinol and PCB 118. Because both studies were corn oil ... aryl hydrocarbon receptor ligands such as PCB 126 and TCDD induced moderate to marked ...

  36. Monograph: Perfluorooctanoic Acid or Perfluorooctane Sulfonate... 7.8MB

    https://ntp.niehs.nih.gov/go/mgraph04

    ... the Faroe Island study corrected for PCBs because the known exposure and ... known or suspected immunotoxicants (e.g., PCBs and other potentially immunomodulatory ...

  37. TR-305: Chlorinated Paraffins (C23, 43Chlorine) (CASRN 108171... 13.3MB

    https://ntp.niehs.nih.gov/go/tr305

    ... of polychlorinated bi- phenyls (PCB's) and chlorinated naphthalenes (Howard et al., 1975). ... For many applications, chlorinated paraffins are being used in place of PCB's (Svanberg ...

  38. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... for Economic Co-operation and Development PAH Polycyclic aromatic hydrocarbon PCB Polychlorinated biphenyl P.L. Public Law pM Picomolar pmol Picomole RBA Relative binding ...

  39. The DNT In Vitro Battery (SACATM 2024 Presentation) 5.0MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-10/3-3_Shafer_SACATM2024_508.pdf

    ... Differentiation (Neurite Outgrowth) Nicotine, Pb, MeHg Schizophrenia (reduced axons and dendrites) Synaptogenesis Triethyltin, Pb, permethrin, PCBs IQ/learning decrements ...

  40. NTP-CERHR Monograph: Potential Human Reproductive and Developmental... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/phthalates/dehp/dehp-monograph.pdf

    .........poly(ADP-ribose).polymerase PCB......polychlorin...ween.phthalate.metabolites.and. polychlorinated.biphenyl.(PCB)-153.on.testicular.function. ...

  41. RoC Profile: Hexachlorobenzene; 15th RoC 2021 155KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/hexachlorobenzene.pdf

    ... Kostyniak PJ, Vena JE. 1999. Comparison of PCB congeners and pesticide levels between ... Case-control study of PCBs, other organochlorines and breast cancer in Eastern Slovakia. ...

  42. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence TR-559 02/25/09 TEF evaluation (PCB 118) 31508-00-6 P Clear Evidence TR-558 02/... Mixture of 3,3',4,4'5-Pentachlorobiphenyl (PCB 126) and 2,3',4,4'5-Pentachlorobiphenyl ...

  43. TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB

    https://ntp.niehs.nih.gov/go/tox077

    ... for 3,3',4,4',5-pentachlorobiphenyl (PCB 126). 106 Briefly, the TEF methodology is a ... study of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) 106 and used relative potency values ...

  44. NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/lead/final/leadappendixa_final_508.pdf

    ... Maternal non-verbal intelligence, breastfeeding status, Hg levels, hemoglobin, PCB-153 ... = 0.8 - 27.1) *sig. correlation with PCB153 Venous blood at testing = 5.4 (5.0) ...

  45. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... for Economic Co-operation and Development PAH Polycyclic aromatic hydrocarbon PCB Polychlorinated biphenyl P.L. Public Law ix List of Abbreviations & Acronyms ICCVAM ...

  46. Presentations at SOT 2025 94KB

    https://ntp.niehs.nih.gov/whatwestudy/niceatm/publications-and-presentations/presentations-at-scientific-meetings/sot-2025

    ... Poster Session: ADME/Toxicokinetics Abstract 4065/Poster K564: Determining species-specific half-lives for all 209 PCB congeners through a Bayesian hierarchical framework and QSAR ...

  47. TR-589: Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade... 7.3MB

    https://ntp.niehs.nih.gov/go/tr589

    ... and with similar potency as PCB-153, but appeared to be a poor substrate for the CYPs 62 . ... biphenyls (PCBs) via breast milk in California: Does BDE-209 transfer to breast milk? ...

  48. Literature Search Results: PFOA or PFOS; May 2016 375KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/pfoa_pfos/literaturesearch_201605_508.pdf

    ... Environ Sci Technol 40(16): 4943-4948. Kannan K, Yun SH, Rudd RJ, Behr M. 2010. High concentrations of persistent organic pollutants including PCBs, DDT, PBDEs and PFOS in little ...

  49. TOX-65: 3,3',4,4'-Tetrachloroazobenzene 2.7MB

    https://ntp.niehs.nih.gov/go/tox065

    ... In addition, a nondioxin-like PCB, 2,2N,4,4N,5,5N-hexachlorobiphenyl (PCB 153), has been shown to reduce epididymal sperm numbers (Waalkens-Berendsen et al., 1996). ...

  50. TOX-66: 3,3',4,4'-Tetrachloroazoxybenzene 3.9MB

    https://ntp.niehs.nih.gov/go/tox066

    ... Toxic equivalency factors for dioxin-like PCBs. Chemosphere 28, 1049-1067. Ahmed, S.A., ... II., pp. 85-112. CRC Press, Inc., Boca Raton, FL. Brandt, I., and Bergman, Å. (1987). PCB ...

 
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