TR-295: Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats... 25.3MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr295.pdf

N W V , , . * b G TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHRYSOTILE ASBESTOS (CAS NO. ... was transferred to the NIEHS. Chrysotile Asbestos, NTP TR 295 NTP TECHNICAL REPORT ON THE ...

TR-279: Amosite Asbestos (CASRN 12172-73-5) in F344/N Rats (Feed... 36.5MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr279.pdf

STUDIES OF AMOSITE ASBESTOS (CAS NO. 12172-73-5) IN F344/N RATS (FEED STUDIES) U.S. ... Amosite Asbestos, NTP TR 279 NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS ...

TR-280: Crocidolite Asbestos (CASRN 12001-28-4) In F344/N Rats... 10.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr280.pdf

CARCINOGENESIS STUDIES OF CROCIDOLITE ASBESTOS (CAS NO. 12001-28-4) IN F344/N RATS ... Crocidolite Asbestos, NTP TR 280 NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS ...

TR-246: Chrysotile Asbestos (CASRN 12001-29-5) in Syrian Golden... 10.0MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr246.pdf

OF CHRYSOTILE ASBESTOS (CAS NO. 12001-29-5) IN SYRIAN GOLDEN HAMSTERS (FEED STUDIES) U.S. ... LIFETIME CARCINOGENESIS STUDIES OF CHRYSOTILE ASBESTOS (CAS NO. 12001-29-5) IN SYRIAN ...

TR-249: Amosite Asbestos (CASRN 12172-73-5) in Syrian Golden... 4.3MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr249.pdf

CARCINOGENESIS STUDIES OF AMOSITE ASBESTOS (CAS NO. 12172-73-5) IN SYRIAN GOLDEN ... LIFETIME CARCINOGENESIS STUDIES OF AMOSITE ASBESTOS (CAS NO. 12172-73-5) IN SYRIAN GOLDEN ...

RoC Profile: Asbestos; 15th RoC 2021 151KB

https://ntp.niehs.nih.gov/ntp/roc/content/profiles/asbestos.pdf

Asbestos CAS No. 1332-21-4 Known to be a human carcinogen First listed in the First Annual Report on Carcinogens (1980) Carcinogenicity Asbestos and all commercial forms of ...

Research Concept for Asbestos; Sept. 2007 158KB

https://ntp.niehs.nih.gov/ntp/noms/final_resconcept/asbestosconcept_508.pdf

NTP Research Concept: Naturally Occurring Asbestos and Related Mineral Fibers Project ... occurring and atypical forms of asbestos were nominated in 2006 by the National ...

Asbestos, amosite: Target Organs and Levels of Evidence for TR... 56KB

https://ntp.niehs.nih.gov/data/tr/200s/tr249levels

2 Asbestos, amosite: Target Organs and Levels of Evidence for TR-249 Lifetime Carcinogenesis Studies of Amosite Asbestos (CASRN 12172-73-5) in Syrian Golden Hamsters (Feed Studies) ...

Abstract for TR-279 62KB

https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr279

Asbestos in F344/N Rats (Feed Studies) CASRN: 12172-73-5 Chemical Formula: (FeC2+Mg)6.Si8O22(OH)2 Report Date: November 1990 Full Report PDF Abstract Amosite Asbestos was ...

Comment: Cleaning Products and Asbestos-containing Cosmetics... 1.7MB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/april/publiccomm/temkin20210416_bsc_508.pdf

and susceptibility of children to cleaning products and asbestos-containing cosmetics. ... chemicals, such as cleaning products and asbestos in talc- based cosmetics. 1. ...

Abstract for TR-249 60KB

https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr249

Asbestos in Syrian Golden Hamsters (Feed Studies) CASRN: 12172-73-5 Chemical Formula: (FeC2+Mg)6. Si8O22(OH)2 Report Date: Nov 1983 Full Report PDF Abstract Amosite Asbestos ...

Abstract for TR-280 61KB

https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr280

Toxicology and Carcinogenesis Studies of Crocidolite Asbestos In F344/N Rats (Feed ... Abstract Carcinogenesis studies of crocidolite asbestos were conducted with male and ...

Abstract for TR-295 65KB

https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr295

Toxicology and Carcinogenesis Studies of Chrysotile Asbestos in F344/N Rats (Feed Studies) ... length chrysotile asbestos were conducted in groups of 88-250 male and female F344/N rats. ...

Abstract for TR-246 62KB

https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr246

Lifetime Carcinogenesis Studies of Chrysotile Asbestos in Syrian Golden Hamsters (Feed ... Full Report PDF Abstract Chrysotile Asbestos was also tested in F344 rats administered in ...

Target Organs and Levels of Evidence for TR-246 58KB

https://ntp.niehs.nih.gov/data/tr/200s/tr246levels

Asbestos (CASRN 12001-29-5) in Syrian Golden Hamsters (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Asbestos, ...

Target Organs and Levels of Evidence for TR-295 60KB

https://ntp.niehs.nih.gov/data/tr/200s/tr295levels

of Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Asbestos, ...

Target Organs and Levels of Evidence for TR-279 57KB

https://ntp.niehs.nih.gov/data/tr/200s/tr279levels

of Amosite Asbestos (CASRN 12172-73-5) in F344/N Rats (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Asbestos, amosite ...

Background Document: RoC: Glass Wool Fibers; 2010 3.7MB

https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/glasswoolbd20100408_508.pdf

... Unlike crystalline fibers, such as asbestos, glass fibers do not split lengthwise into ... due to the structural similarity between glass wool, other SVFs, and asbestos. ...

Target Organs and Levels of Evidence for TR-280 56KB

https://ntp.niehs.nih.gov/data/tr/200s/tr280levels

of Crocidolite Asbestos (CASRN 12001-28-4) in F344/N Rats (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Asbestos, crocidolite ...

Minutes: BSC; June 22, 2007 162KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2007/june/bsc_mins2007june22_508.pdf

......... 13 3. Asbestos, Naturally Occurring and Atypical Forms ... animals and it was of low priority. 3. Asbestos, Naturally Occurring and Atypical Forms ...

Glass Wool Fibers Expert Panel Report Part A - Peer Review of... 911KB

https://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/june/gwf_parta.pdf

... before and after adjusting for asbestos exposure, including dose-response trends. ... to SVF (not otherwise classified) and asbestos, and to estimate quantitative average ...

TR-277: Tremolite (CASRN 14567-73-8) in F344/N Rats (Feed Studies... 10.7MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr277.pdf

... "asbestos" has a commercial/industrial derivation limited to naturally occurring fibrous minerals of the serpentine or amphibole series. Chrysotile is the only type of asbestos ...

Public Health Impact 1.5MB

https://ntp.niehs.nih.gov/media/impact

... Type: Proposed Rule August 01, 2023 88 FR 50444 7439-92-1 2023 EPA Asbestos; Reporting and ... and recordkeeping requirements for asbestos under the Toxic Substances Control Act (TSCA). ...

15th RoC: Appendix F 174KB

https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

acid amide see Acrylamide actinolite see Asbestos actinon see Ionizing Radiation, Radon ... aminotriazole see Amitrole amosite see Asbestos analgesic mixtures containing phenacetin ...

RoC Background Document: Silica, Crystalline (Respirable Size... 1.7MB

https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/silica_no_app_508.pdf

... for smoking or asbestos exposure, so confounding is unlikely to explain these results. ... and stone products 270 27 Abrasive, asbestos, and miscellaneous nonmetallic mineral ...

Minutes: BSC TRRS; July 27, 1984 719KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1984/july/84jul27trrsmins_508.pdf

Technical Report CAS No. Benzene 71-43-2 C h r y s o t i l e Asbestos 12001-29-5 ... C h r y s o t i l e Asbestos. D r . Jones, a p r i n c i p a l reviewer f o r t h e t e c ...

RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB

https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf

... The increased relative risk is not readily explained by confounding by smoking or asbestos ... The increased risk is not readily explained by confounding by either smoking or asbestos ...

Glass Wool Fibers Expert Panel Report Part B - Recommendation... 801KB

https://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/june/gwf_partb.pdf

... confounding from tobacco use and asbestos exposure and Baccarelli et al. (2006) ... Mesothelioma is strongly linked to asbestos, and is extremely rare without this exposure. ...

Minutes: BSC TRRS; Feb 28, 1983 601KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1983/feb/83feb28trrsmins_508.pdf

Ethoxylated dodecyl a1 coho1 Asbestos, croci do1 i t e Benzyl a c e t a t e C A S No. ... F r i e s s and Swenberg), and one a b s t e n t i o n (Dr. Scala). Asbestos, c r o c i d ...

Minutes: BSC; March 27, 1984 3.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf

Overview of NCTR Director's Laboratory 9 (1) Modulation of Asbestos Cytotoxicity 9 (2) ... of agent toxicity . (1) Modulation of Asbestos Cytotoxicity : He discussed the basis ...

Comment: National Toxicological Program (NTP) Board of Scientific... 1.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/05_kennedy_bsc_508.pdf

Paradigms are not easy things to change: for example . Asbestos was linked to cancer in the 1930's . Asbestos was removed from intra oral bandages in 1980 . Lead was introduced for ...

Human Cancer Studies; Suril Mehta; RoC; Jan. 24, 2018 644KB

https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/presentations/humancancerstudies_508.pdf

polycyclic aromatic hydrocarbons (PAHs), asbestos - Non-occupational: current and past ... Potential confounders among stomach cancer risk factors - Occupational: lead, asbestos - ...

Listed Substances; 15th RoC 2021 76KB

https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

Containing Phenacetin) Aristolochic Acids Arsenic and Inorganic Arsenic Compounds Asbestos Azathioprine Benzene Benzidine (see Benzidine and Dyes Metabolized to Benzidine) ...

Presentation: Cobalt and Certain Cobalt Compounds Human Cancer... 479KB

https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/humancancerstudies_508.pdf

59.8 37.8 Relevant confounders among lung cancer risk factors - Occupational: asbestos, chromium, nickel, arsenic, soot, tar or radon. - Non-occupational: current and past ...

Occupational and Inhalation Exposures Program; BSC; April 23... 195KB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/april/meeting_materials/oie_bsc_508.pdf

... Ongoing and Continuing Interactions Stakeholder Issue Role of Stakeholder ATSDR Community exposures to naturally occurring asbestos Partner, user NIOSH Asbestos, alpha-pinene, ...

RoC Profile: Diesel Exhaust Particulates; 15th RoC 2021 151KB

https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dieselexhaustparticulates.pdf

The increased risk was not readily explained by confounding from smoking or exposure to asbestos. However, only some studies used quantitative or semi-quantitative assessments of ...

National Institute of Environmental Health Sciences: Combined... 154KB

https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/exposure/combined

psychosocial stress) throughout their lifetimes, and there is clear evidence that combined exposures can have cumulative effects (e.g., asbestos and tobacco smoke on lung cancer). ...

RoC Background Document: Alcoholic Beverage Consumption; Dec... 5.3MB

https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/05alcoholicbevcon_508.pdf

... aflatoxins, ethyl carbamate, asbestos, and arsenic compounds (Table 1-1). 1.2 ... Asbestos fibers have been identified in Canadian and U.S. beers (Cunningham and ...

TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf

... human level for talc containing no asbestos fibers is 2 mg/m3 and thought that this ... Commercial talc is categorized into cosmetic grade, which is free o f asbestos, and ...

TOX-74: Cellulose Insulation 7.9MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox074_rev.pdf

... promotion of CI as a safe alternative to asbestos, and the lack of data on the potential ... Spray-applied CI has been used to cover and protect from existing asbestos-containing ...

Appendix G; 15th RoC 2021 73KB

https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

... 1327-53-3 (arsenic trioxide) see Arsenic and Inorganic Arsenic Compounds 1332-21-4 see Asbestos 1333-82-0 (chromium trioxide) see Chromium Hexavalent Compounds 1335-32-6 (lead ...

RoC Profile: Certain Glass Wool Fibers (Inhalable); 15th RoC... 235KB

https://ntp.niehs.nih.gov/ntp/roc/content/profiles/glasswoolfibers.pdf

... glass wool exposure and mesothelioma, a rare cancer strongly linked to asbestos exposure. ... et al. 2001) or did not evaluate co-exposure to asbestos (Boffetta et al. 1997). ...

RoC Profile: Silica, Crystalline (Respirable Size); 15th RoC... 136KB

https://ntp.niehs.nih.gov/ntp/roc/content/profiles/silica.pdf

4.0. Elevated risks have been seen in stud- ies that accounted for smoking or asbestos exposure, and confound- ing by co-exposure is unlikely to explain these results (IARC 1997). ...

Occupational and Inhalation Exposures Program; Kristen Ryan;... 3.4MB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/april/presentations/oie_bsc_presentation_508.pdf

Mold (Aspergillus fumigatus) Nanomaterials (multi-wall carbon nanotubes) Radiofrequency radiation Asbestos fibers Chemical reagents (trimethylsilyldiazomethane) Design & Conduct ...

Ear, Epithelium - Hyperplasia - Nonneoplastic Lesion Atlas 292KB

https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/ear/Epithelium-Hyperplasia

National Toxicology Program. 1985. NTP TR-295. Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CAS No. 12001-29-5) in F344/N Rats (Feed Studies). NTP, Research ...

Research Program Introductions for DNTP/NIEHS; BSC; Dec. 3-4... 221KB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2020/december/meeting_materials/3berridge_bsc_508.pdf

... psychosocial stress) throughout their lifetimes and there is clear evidence that combined exposures can have cumulative effects (e.g., asbestos and tobacco smoke on lung cancer). ...

Minutes: BSC RoC; Dec. 13-15, 2000 205KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/minutes20001213.pdf

... Quartz, and trace amounts of "other" asbestiform fibers, but should not contain asbestos. ... Zahm noted that the six minerals classified as asbestos can exist without being ...

Ear, Epithelium - Hyperplasia 642KB

https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/ear/ephyperp/ear-epithelium-hyperplasia_508.pdf

.../full National Toxicology Program. 1985. NTP TR-295. Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CAS No. 12001-29-5) in F344/N Rats (Feed Studies). ...

Combined Exposures and Mixtures Program; BSC; Feb. 2, 2021 277KB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/february/meeting_materials/cem_bsc_508.pdf

... psychosocial stress) throughout their lifetimes and there is clear evidence that combined exposures can have cumulative effects (e.g., asbestos and tobacco smoke on lung cancer). ...

National Institute of Environmental Health Sciences: Occupational... 156KB

https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/exposure/occupational

... Occurring Asbestos and Related Mineral Fibers This project involves method development for fiber studies, characterization of the inhalational toxicity of asbestos exposure in ...