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336 results found for "bha".
  1. RoC Profile: Butylated Hydroxyanisole; 15th RoC 2021 132KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/butylatedhydroxyanisole.pdf

    Butylated Hydroxyanisole CAS No. 25013-16-5 Reasonably anticipated to be a human carcinogen First listed in the Sixth Annual Report on Carcinogens (1991) Also known as BHA or or ...

  2. Abstract for TR-524 71KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr524

    Organic acids with hydroxy groups on the second carbon from the carbonyl carbon are referred to as beta-hydroxy acids (BHA). Both AHA and BHA are used to treat various skin ...

  3. RoC Profile: Diesel Exhaust Particulates; 15th RoC 2021 151KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dieselexhaustparticulates.pdf

    diesel exhaust (IARC 1989, Cohen and Higgins 1995, Bha- tia et al. 1998). Meta-analyses by Cohen and Higgins (1995) and Bha- tia et al. (1998) suggested an overall relative risk ...

  4. TOX-70: p-tert-Butylcatechol (CASRN 98-29-3) 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox070.pdf

    ... The analogs caffeic acid and butylated hydroxyanisole (BHA) were weak carcinogens in the ... with that of similar antioxidants, BHA and BHT, which are added to food. ...

  5. TR-524: Photocarcinogenesis Study of Glycolic Acid and Salicylic... 17.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr524.pdf

    ... Organic acids with hydroxy groups on the second carbon from the carbonyl carbon are referred to as beta-hydroxy acids (BHA). Both AHA and BHA are used to treat various skin con- ...

  6. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... Be see Beryllium and Beryllium Compounds BHA see Butylated Hydroxyanisole B[j]F see ... 2-tert-butyl-4-hydroxyanisole (2-BHA) see Butylated Hydroxyanisole ...

  7. Stokes: Current and Future Contributions of NICEATM and ICCVAM... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/7thwc/ms/reb4-stokes1.pdf

    ... ICCVAM and NICeAtM also have liaisons contributing to two JaCVAM-led validation studies: the in vivo/in vitro comet assay and the BHAS cell transformation assay. 4 Independent ...

  8. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... Chemotherapeutic Agents 23214-92-8 see Adriamycin 23246-96-0 see Riddelliine 25013-16-5 see Butylated Hydroxyanisole 25316-40-9 (doxorubicin hydrochloride) see Adriamycin ...

  9. Background Document: Styrene oxide; BSC RoC, Jan. 20-21, 2000 267KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bg_styrene_oxide_508.pdf

    ... Additional rats received diets containing 0%, 0.5%, 1%, or 2% butylated hydroxyanisole (BHA) as a positive control treatment. (BHA is a widely used food additive [antioxidant] and ...

  10. TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB

    https://ntp.niehs.nih.gov/go/tr371

    ... on BHA-induced forestomach carcinogene- sis, Ito exposed groups of 15 F344 rats to 2% ben- zoic acid in the diet for 52 weeks with and without 2% butylated hydroxyanisole (BHA) ...

  11. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... Be see Beryllium and Beryllium Compounds BHA see Butylated Hydroxyanisole B[j]F see ... 2-tert-butyl-4-hydroxyanisole (2-BHA) see Butylated Hydroxyanisole ...

  12. TOX-27: Riddelliine (CASRN 23246-96-0) 3.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox027.pdf

    ... Presumably, the sulfhydryls bind the toxic metabolites of PAs and minimize the amount of toxicant available to cause tissue damage. Administration of antioxidants such as BHA or ...

  13. DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart07_508.pdf

    ... <10.0 1 Nitrite Nitrogen b,c (ppm) <0.61 1 BHA b,d (ppm) <1.0 1 BHT b,d (ppm) <1.0 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  14. Summary Minutes SACATM Meeting Sept. 16, 2014 271KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2014/september/minutes20140916_508.pdf

    ... He described the Cell Transformation Assay based on the Bhas 42 cell line, which is used to evaluate carcinogenicity, noting that it can be used to replace animal testing. He ...

  15. TR-459: t-Butylhydroquinone (CASRN 1948-33-0) in F344 Rats and... 25.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr459.pdf

    ... lesions in the forestomach of rats by 3-tert-butyl-4-hydroxyanisole (BHA). Food Chem. ... Mutagenicity of 3-tert- butyl-4-hydroxyanisole (BHA) and its metabolites in short-term ...

  16. TOX-103: Select Ionic Liquids (1-Ethyl-3-Methylimidazolium Chloride... 4.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox103_508.pdf

    ... b 10 1 Nitrite Nitrogen (ppm) a,b <0.61 1 BHA (ppm) a,c <1.00 1 BHT (ppm) a,c <1.00 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  17. TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf

    ... 14.2 1 Nitrite Nitrogen (ppm) a,b <0.61 1 BHA (ppm) a,c <1.0 1 BHT (ppm) a,c <1.0 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  18. TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf

    ... 4 Nitrite Nitrogen (ppm) a,b <0.61 - 4 BHA (ppm) a,c <1.0 - 4 BHT (ppm) a,c <1.0 - 4 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  19. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... (Sigma-Aldrich, Milwaukee, WI) 25013-16-5 2/8/2016 500 mg 99.9 White Crystals ... 204.27 Butylated Hydroxyanisole 25013-16-5 180.25 Butylated Hydroxytoluene ...

  20. Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  21. TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  22. TOX-98: Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN... 3.0MB

    https://ntp.niehs.nih.gov/go/tox098

    ... 8 Nitrite Nitrogen (ppm) a,b <0.61 - 8 BHA (ppm) a,c <1.0 - 8 BHT (ppm) a,c <1.0 - 8 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  23. TOX-9: Cresols (CASRNs 95-48-7, 108-39-4, 106-44-5) 6.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox009.pdf

    ... antioxidant 3-tert-butyl-4-hydroxyanisole (BHA) induces mild hyperplasia and ... Earlier studies by Ito et al (1983) demonstrated that 2 % dietary BHA is carcinogenic in ...

  24. TOX-106: Sodium Metavanadate (CASRN 13718-26-8) and Vanadyl Sulfate... 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox106_508.pdf

    ... 3 Nitrite Nitrogen (ppm) a,b <0.61 - 3 BHA (ppm) a,c <1.0 - 3 BHT (ppm) a,c <1.0 - 3 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  25. Draft RoC Monograph for ortho-Toluidine: Literature Search Strategy... 1.1MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/otol_literaturesearch20130815_508.pdf

    ... YM, Yamazaki S, Umeda M, Tanaka N. 2010. A Bhas 42 cell transformation assay on 98 chemicals: The characteristics and performance for the prediction of chemical carcinogenicity. ...

  26. TR-550: Cresols (CASRN 1319-77-3) in Male F344/N Rats and Female... 3.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr550.pdf

    ... For example, butylated hydroxyanisole (BHA), non-DNA reactive and a skin irritant, ... 27.0 23 Nitrite nitrogen (ppm) c <0.89 23 BHA (ppm) d <1.0 23 BHT (ppm) d <1.0 23 Aerobic ...

  27. DART-01: Prenatal Development Studies of Tris(chloropropyl) Phosphate... 937KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart01_508.pdf

    ... - 1 Nitrite Nitrogen (ppm) c <0.61 - 1 BHA (ppm) d <1.0 - 1 BHT (ppm) d <1.0 - 1 ... II <0.01 - 1 Endosulfane Sulfate <0.03 - 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  28. DART-02: Prenatal Development Studies of 4-Methylcyclohexanemethanol... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart02_508.pdf

    ... 10 1 Nitrite Nitrogen c (ppm) <0.61 1 BHA d (ppm) 2.37 1 BHT d (ppm) <1.0 1 Aerobic ... II <0.01 1 Endosulfane Sulfate <0.03 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  29. DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf

    ... 2 Nitrite Nitrogen (ppm) c <0.61 - 2 BHA (ppm) d <1.0 - 2 BHT (ppm) d <1.0 - 2 ... II <0.01 - 2 Endosulfan Sulfate <0.03 - 2 BHA = butylated hydroxyanisole; BHT = butylated ...

  30. DART-03: Prenatal Development Studies of Vinpocetine (CASRN 42971... 1.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart03_508.pdf

    ... c 9.65 1 Nitrite Nitrogen (ppm) c <0.61 1 BHA (ppm) d <1.0 1 BHT (ppm) d <1.0 1 Aerobic ... II <0.01 1 Endosulfane sulfate <0.03 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  31. TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox077_508.pdf

    ... 1 Nitrite Nitrogen (ppm) a,b <0.61 - 1 BHA (ppm) a,c <1.0 - 1 BHT (ppm) a,c <1.0 - 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  32. TOX-101: Trimethylsilyldiazomethane (CASRN 18107-18-1) Administered... 6.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox101_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.00 - 2 BHT (ppm) a,c <1.00 - 2 ... a <0.01 - 2 Endosulfan Sulfate a <0.03 - 2 BHA = butylated hydroxyanisole; BHT = butylated ...

  33. Draft TR-599: Sodium Tungstate Dihydrate (CASRN 10213-10-2) in... 3.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr599_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  34. Draft TR-601: Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered... 3.6MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr601_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  35. TR-599: Sodium Tungstate Dihydrate in Sprague Dawley (Hsd:Sprague... 4.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr599_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  36. TR-601: Di(2-ethylhexyl) Phthalate Administered in Feed to Sprague... 4.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr601_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  37. Minutes: SACATM; June 17, 2011 343KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2011/june/minutes20110617.pdf

    ... or international peer review, e.g., the Bhas cell transformation assay and the LabCyte ... transformation assay in a BHAS42 cell line for the assessment of carcinogenic potential. ...

  38. TR-602: Isomeric Mixture of Tris(chloropropyl) Phosphate Administered... 8.0MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-06/tr602_508.pdf

    ... 4 Nitrite Nitrogen (ppm) a,b <0.61 - 4 BHA (ppm) a,c <1.0 - 4 BHT (ppm) a,c <1.0 - 4 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  39. ICCVAM Biennial Progress Report 2008-2009 11.8MB

    https://ntp.niehs.nih.gov/iccvam/docs/annrpt/biennialrpt2010-508r.pdf

    ... Carcinogen Testing . Validation study of the Bhas 42 cell transformation assay to screen chemicals for carcinogenic potential - NICEATM and ICCVAM have liaison members to the ...

  40. IMM-01: Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclo... 969KB

    https://ntp.niehs.nih.gov/ntp/htdocs/imm/imm001_508.pdf

    ... 3 Nitrate Nitrogen (ppm) c 11.51 ± 2.18 10.0-14.0 3 Nitrite Nitrogen (ppm) c 0.61 - 3 BHA (ppm) d 1.41 ± 0.72 1.0-2.24 3 BHT (ppm) d <1.0 - 3 Aerobic Plate Count (CFU/g) <10 - 3 ...

  41. Draft DART-06: Modified One-Generation Study of 2-Ethylhexyl... 2.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/dart06_508.pdf

    ... 5 Nitrite Nitrogen (ppm) a,b <1.0 - 5 BHA (ppm) a,c <1.0 - 5 BHT (ppm) a,c <1.0 - 5 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  42. DART-06: Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnam... 5.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart06_508.pdf

    ... 5 Nitrite Nitrogen (ppm) a,b <1.0 - 5 BHA (ppm) a,c <1.0 - 5 BHT (ppm) a,c <1.0 - 5 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  43. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox99_508.pdf

    ... 5 Nitrate Nitrogen (ppm) c 22.54 ± 12.0 10.0-35.9 5 Nitrite Nitrogen (ppm) c 0.61 - 5 BHA (ppm) d <1.0 - 5 BHT (ppm) d <1.0 - 5 Aerobic Plate Count (CFU/g) <10.0 - 5 Coliform ...

  44. TR-294: Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr294.pdf

    ... Selenium (ppm) Aflatoxins (ppb) (b,c) Nitrate nitrogen (ppm) (d,e) Nitrite nitrogen (ppm) (d,e) BHA (ppm) (f,g) BHT (ppm) (0 Aerobic plate count (CFUlg) (h) Coliform (MPN/g) (ij) ...

  45. TR-381: d-Carvone (CASRN 2244-16-8) in B6C3F1Mice (Gavage Studies... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr381.pdf

    ... (ppm) (b) 9.03 k 4.76 0.10-22.0 Nitrite nitrogen (ppm) (b) 1.66 f 1.76 0.10-7.10 BHA (ppm) (c) 4.08 f 4.76 2.00-17.0 BHT (ppm) (c) 2.68 f 2.55 1.00-12.0 Aerobic plate count ...

  46. TOX-89: Toxicity Studies of 5-Amino-o-cresol (CASRN 2835-95-2... 2.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox089_508.pdf

    ... (ppm) c 14.6 ± 6.6 5.09-23.7 5 Nitrite nitrogen (ppm) c 1.34 ± 1.34 0.30-3.04 5 BHA (ppm) d <1.0 - 5 BHT (ppm) d <1.0 - 5 Aerobic plate count (CFU/g) 10 ± 0.0 10 5 ...

  47. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox99_508.pdf

    ... 5 Nitrate Nitrogen (ppm) c 22.54 ± 12.0 10.0-35.9 5 Nitrite Nitrogen (ppm) c 0.61 - 5 BHA (ppm) d <1.0 - 5 BHT (ppm) d <1.0 - 5 Aerobic Plate Count (CFU/g) <10.0 - 5 Coliform ...

  48. RoC Monograph: ortho-Toluidine; July 2014 2.4MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/otoluidine_508.pdf

    ... Lim YM, Yamazaki S, Umeda M et al. 2010. A Bhas 42 cell transformation assay on 98 ... - + 330 150 Matthews et al. (1985) Mouse Bhas 42 b initiation assay promotion assay - + ...

  49. TR-288: 1,3-Butadiene (CASRN 106-99-0) in B6C3F1Mice (Inhalation... 5.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr288.pdf

    ... Selenium (ppm) Aflatoxins(ppb) Nitrate nitrogen ( c ) (ppm) Nitrite nitrogen ( c ) (ppm) BHA Id1 - (nom) BHT (d) (&m) Aerobic plate count tCFU/g) Coliform (MPN/e)If, E. coli tMPN/...

  50. TR-325: Pentachloronitrobenzene (CASRN 82-68-8) in B6C3F1Mice... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr325.pdf

    ... (ppm) Aflatoxins (ppb) (b) Nitrate nitrogen (ppm) (c) Nitrite nitrogen (ppm) (c) BHA (ppm) (d) BHT (ppm) (d) Aerobic plate count (CFUlg) (e) Coliform (MPN/g) (D E. coli ...

 
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