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351 results found for "bha".
  1. Butylated hydroxyanisole (BHA) M88172 21KB

    https://ntp.niehs.nih.gov/go/ts-m88172

    Butylated hydroxyanisole (BHA) M88172 CASRN: 25013-16-5 Formula: C11-H16-O2 Synonyms/Common Names BHA tert-Butyl-4-methoxyphenol Genetic Toxicology Micronucleus (A65600) Completed ...

  2. Nomination Summary for BHA (N20509) 19KB

    https://ntp.niehs.nih.gov/go/nm-n20509

    BHA (N20509) Nominated Substances: Butylated hydroxyanisole (BHA) Nomination Date: 12/05/2004 Nominator: Private Individual Rationale: BHA is a widely used preservative in pet ...

  3. RoC Profile: Butylated Hydroxyanisole; 15th RoC 2021 132KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/butylatedhydroxyanisole.pdf

    Butylated Hydroxyanisole CAS No. 25013-16-5 Reasonably anticipated to be a human carcinogen First listed in the Sixth Annual Report on Carcinogens (1991) Also known as BHA or or ...

  4. Nomination Summary for Chemicals id by IARC as possible carcinogens... 30KB

    https://ntp.niehs.nih.gov/go/nm-n87322

    Nominated Substances: p-Aminoazobenzene, o-Aminoazotoluene, Auramine, Benzyl violet 4B, Butylated hydroxyanisole (BHA), beta-Butyrolactone, C.I. Solvent Red 80 (8CI), ...

  5. Abstract for TR-524 32KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr524/index.html

    Organic acids with hydroxy groups on the second carbon from the carbonyl carbon are referred to as beta-hydroxy acids (BHA). Both AHA and BHA are used to treat various skin ...

  6. Nomination Summary for t-butylhydroquinone (N85325) 19KB

    https://ntp.niehs.nih.gov/go/nm-n85325

    Rationale: Potential for increased use because of questions about safety of phenolic antioxidants Butylated hydroxyanisole (BHA) and Butylated hydroxytoluene (BHT), available ...

  7. RoC Profile: Diesel Exhaust Particulates; 15th RoC 2021 151KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dieselexhaustparticulates.pdf

    diesel exhaust (IARC 1989, Cohen and Higgins 1995, Bha- tia et al. 1998). Meta-analyses by Cohen and Higgins (1995) and Bha- tia et al. (1998) suggested an overall relative risk ...

  8. TOX-70: p-tert-Butylcatechol (CASRN 98-29-3) 4.6MB

    https://ntp.niehs.nih.gov/go/tox070

    ... The analogs caffeic acid and butylated hydroxyanisole (BHA) were weak carcinogens in the rat forestomach epithelium; butylated hydroxytoluene (BHT) was not carcinogenic (Hirose et ...

  9. TR-524: Photocarcinogenesis Study of Glycolic Acid and Salicylic... 17.0MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr524.pdf

    ... Organic acids with hydroxy groups on the second carbon from the carbonyl carbon are referred to as beta-hydroxy acids (BHA). Both AHA and BHA are used to treat various skin con- ...

  10. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... Be see Beryllium and Beryllium Compounds BHA see Butylated Hydroxyanisole B[j]F see ... 2-tert-butyl-4-hydroxyanisole (2-BHA) see Butylated Hydroxyanisole ...

  11. Substance Search 454KB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/status/index.html

    ... tert-Butylamine n-Butyl-p-aminobenzoate Butyl anthranilate Butylated hydroxyanisole (BHA) Butylated hydroxytoluene N-Butylbenzenesulfonamide Butyl benzyl phthalate ...

  12. Stokes: Current and Future Contributions of NICEATM and ICCVAM... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/7thwc/ms/reb4-stokes1.pdf

    ... ICCVAM and NICeAtM also have liaisons contributing to two JaCVAM-led validation studies: the in vivo/in vitro comet assay and the BHAS cell transformation assay. 4 Independent ...

  13. Background Document: Styrene oxide; BSC RoC, Jan. 20-21, 2000 267KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bg_styrene_oxide_508.pdf

    ... Additional rats received diets containing 0%, 0.5%, 1%, or 2% butylated hydroxyanisole (BHA) as a positive control treatment. (BHA is a widely used food additive [antioxidant] and ...

  14. Nomination Background: Ethoxyquin (CASRN: 91-53-2) 3.0MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ethoxyquin_508.pdf

    ... During the second week, butylated hydroxy-anisole (BHA) was also added to the test diet, and food intake was measured . BHA-induced epithelial hyperplasia in the forestomach was ...

  15. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... Chemotherapeutic Agents 23214-92-8 see Adriamycin 23246-96-0 see Riddelliine 25013-16-5 see Butylated Hydroxyanisole 25316-40-9 (doxorubicin hydrochloride) see Adriamycin ...

  16. TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr371.pdf

    ... on BHA-induced forestomach carcinogene- sis, Ito exposed groups of 15 F344 rats to 2% ben- zoic acid in the diet for 52 weeks with and without 2% butylated hydroxyanisole (BHA) ...

  17. TOX-27: Riddelliine (CASRN 23246-96-0) 3.4MB

    https://ntp.niehs.nih.gov/go/tox027

    ... Presumably, the sulfhydryls bind the toxic metabolites of PAs and minimize the amount of toxicant available to cause tissue damage. Administration of antioxidants such as BHA or ...

  18. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... Be see Beryllium and Beryllium Compounds BHA see Butylated Hydroxyanisole B[j]F see ... 2-tert-butyl-4-hydroxyanisole (2-BHA) see Butylated Hydroxyanisole ...

  19. DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart07_508.pdf

    ... <10.0 1 Nitrite Nitrogen b,c (ppm) <0.61 1 BHA b,d (ppm) <1.0 1 BHT b,d (ppm) <1.0 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  20. Nomination Background: p-tert-Butylcatechol 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/butylcatechol_508.pdf

    ... Finally, Hirose ti al. (1988) reported that analogs, caffeic acid and BHA were weak carcinogens in rat f orestomach epithelium; BHT was negative in this study. 16 Prepared for NCI ...

  21. Summary Minutes SACATM Meeting Sept. 16, 2014 271KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2014/september/minutes20140916_508.pdf

    ... He described the Cell Transformation Assay based on the Bhas 42 cell line, which is used to evaluate carcinogenicity, noting that it can be used to replace animal testing. He ...

  22. TOX-103: Toxicity Studies of Select Ionic Liquids (1-Ethyl-3... 4.7MB

    https://ntp.niehs.nih.gov/go/tox103

    ... b 10 1 Nitrite Nitrogen (ppm) a,b <0.61 1 BHA (ppm) a,c <1.00 1 BHT (ppm) a,c <1.00 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  23. TR-459: t-Butylhydroquinone (CASRN 1948-33-0) in F344 Rats and... 25.3MB

    https://ntp.niehs.nih.gov/go/tr459

    ... lesions in the forestomach of rats by 3-tert-butyl-4-hydroxyanisole (BHA). Food Chem. ... Mutagenicity of 3-tert- butyl-4-hydroxyanisole (BHA) and its metabolites in short-term ...

  24. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... (Sigma-Aldrich, Milwaukee, WI) 25013-16-5 2/8/2016 500 mg 99.9 White Crystals ... 204.27 Butylated Hydroxyanisole 25013-16-5 180.25 Butylated Hydroxytoluene ...

  25. TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB

    https://ntp.niehs.nih.gov/go/tox102

    ... 14.2 1 Nitrite Nitrogen (ppm) a,b <0.61 1 BHA (ppm) a,c <1.0 1 BHT (ppm) a,c <1.0 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  26. TR-600: Toxicology and Carcinogenesis Studies of Di-n-butyl Phthalate... 3.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  27. Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  28. Draft RoC Monograph for ortho-Toluidine: Literature Search Strategy... 1.1MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/otol_literaturesearch20130815_508.pdf

    ... YM, Yamazaki S, Umeda M, Tanaka N. 2010. A Bhas 42 cell transformation assay on 98 chemicals: The characteristics and performance for the prediction of chemical carcinogenicity. ...

  29. TOX-9: Cresols (CASRNs 95-48-7, 108-39-4, 106-44-5) 6.1MB

    https://ntp.niehs.nih.gov/go/tox009

    ... antioxidant 3-tert-butyl-4-hydroxyanisole (BHA) induces mild hyperplasia and ... Earlier studies by Ito et al (1983) demonstrated that 2 % dietary BHA is carcinogenic in ...

  30. Nomination Background: Butyl Paraben (CASRN: 94-26-8) 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/butylparaben_508.pdf

    ... However, parabens were lumped together with butylated hydroxyanisole (BHA), phytoestrogens, and synthetic steroids. Of the occupations listed with possible exposure to parabens, ...

  31. DART-01: Prenatal Development Studies of Tris(chloropropyl) Phosphate... 937KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart01_508.pdf

    ... - 1 Nitrite Nitrogen (ppm) c <0.61 - 1 BHA (ppm) d <1.0 - 1 BHT (ppm) d <1.0 - 1 ... II <0.01 - 1 Endosulfane Sulfate <0.03 - 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  32. DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf

    ... 2 Nitrite Nitrogen (ppm) c <0.61 - 2 BHA (ppm) d <1.0 - 2 BHT (ppm) d <1.0 - 2 ... II <0.01 - 2 Endosulfan Sulfate <0.03 - 2 BHA = butylated hydroxyanisole; BHT = butylated ...

  33. TR-550: Cresols (CASRN 1319-77-3) in Male F344/N Rats and Female... 3.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr550.pdf

    ... For example, butylated hydroxyanisole (BHA), non-DNA reactive and a skin irritant, produces a low incidence of carcinoma in the forestomach of rodents, presumably as a result of ...

  34. TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB

    https://ntp.niehs.nih.gov/go/tox077

    ... 1 Nitrite Nitrogen (ppm) a,b <0.61 - 1 BHA (ppm) a,c <1.0 - 1 BHT (ppm) a,c <1.0 - 1 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  35. TOX-101: Trimethylsilyldiazomethane (CASRN 18107-18-1) Administered... 6.7MB

    https://ntp.niehs.nih.gov/go/tox101

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.00 - 2 BHT (ppm) a,c <1.00 - 2 ... a <0.01 - 2 Endosulfan Sulfate a <0.03 - 2 BHA = butylated hydroxyanisole; BHT = butylated ...

  36. DART-02: Prenatal Development Studies of 4-Methylcyclohexanemethanol... 1.1MB

    https://ntp.niehs.nih.gov/go/dart02

    ... 10 1 Nitrite Nitrogen c (ppm) <0.61 1 BHA d (ppm) 2.37 1 BHT d (ppm) <1.0 1 Aerobic ... II <0.01 1 Endosulfane Sulfate <0.03 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  37. DART-02: Prenatal Development Studies of 4-Methylcyclohexanemethanol... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart02_508.pdf

    ... 10 1 Nitrite Nitrogen c (ppm) <0.61 1 BHA d (ppm) 2.37 1 BHT d (ppm) <1.0 1 Aerobic ... II <0.01 1 Endosulfane Sulfate <0.03 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  38. Nomination Background: 3,4-Dihydroxycinnamic acid (CASRN: 331... 2.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/chlorogenicacid_508.pdf

    ... 1997. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and ... 1997. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and ...

  39. DART-03: Prenatal Development Studies of Vinpocetine (CASRN 42971... 1.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart03_508.pdf

    ... c 9.65 1 Nitrite Nitrogen (ppm) c <0.61 1 BHA (ppm) d <1.0 1 BHT (ppm) d <1.0 1 Aerobic ... II <0.01 1 Endosulfane sulfate <0.03 1 BHA = butylated hydroxyanisole; BHT = butylated ...

  40. TR-601: Toxicology and Carcinogenesis Studies of Di(2-ethylhexyl... 4.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr601_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  41. TR-599: Toxicology and Carcinogenesis Studies of Sodium Tungstate... 4.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr599_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  42. Draft TR-599: Sodium Tungstate Dihydrate (CASRN 10213-10-2) in... 3.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr599_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  43. Draft TR-601: Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered... 3.6MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr601_508.pdf

    ... 2 Nitrite Nitrogen (ppm) a,b <0.61 - 2 BHA (ppm) a,c <1.0 - 2 BHT (ppm) a,c <1.0 - 2 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  44. Minutes: SACATM; June 17, 2011 343KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2011/june/minutes20110617.pdf

    ... or international peer review, e.g., the Bhas cell transformation assay and the LabCyte ... transformation assay in a BHAS42 cell line for the assessment of carcinogenic potential. ...

  45. IMM-01: Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclo... 969KB

    https://ntp.niehs.nih.gov/go/imm001

    ... 3 Nitrate Nitrogen (ppm) c 11.51 ± 2.18 10.0-14.0 3 Nitrite Nitrogen (ppm) c 0.61 - 3 BHA (ppm) d 1.41 ± 0.72 1.0-2.24 3 BHT (ppm) d <1.0 - 3 Aerobic Plate Count (CFU/g) <10 - 3 ...

  46. ICCVAM Biennial Progress Report 2008-2009 11.8MB

    https://ntp.niehs.nih.gov/iccvam/docs/annrpt/biennialrpt2010-508r.pdf

    ... Carcinogen Testing . Validation study of the Bhas 42 cell transformation assay to screen chemicals for carcinogenic potential - NICEATM and ICCVAM have liaison members to the ...

  47. TOX-89: Toxicity Studies of 5-Amino-o-cresol (CASRN 2835-95-2... 2.5MB

    https://ntp.niehs.nih.gov/go/tox089

    ... (ppm) c 14.6 ± 6.6 5.09-23.7 5 Nitrite nitrogen (ppm) c 1.34 ± 1.34 0.30-3.04 5 BHA (ppm) d <1.0 - 5 BHT (ppm) d <1.0 - 5 Aerobic plate count (CFU/g) 10 ± 0.0 10 5 ...

  48. DART-06: Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnam... 5.2MB

    https://ntp.niehs.nih.gov/go/dart06

    ... 5 Nitrite Nitrogen (ppm) a,b <1.0 - 5 BHA (ppm) a,c <1.0 - 5 BHT (ppm) a,c <1.0 - 5 ... BHA = butylated hydroxyanisole; BHT = butylated hydroxytoluene; CFU = colony-forming ...

  49. TOX-80: Sodium Thioglycolate (CASRN 367-51-1) Administered Dermally... 3.5MB

    https://ntp.niehs.nih.gov/go/tox080

    ... (ppb) <5.00 1 Nitrate nitrogen (ppm) c 18.8 1 Nitrite nitrogen (ppm) c <0.61 1 BHA (ppm) d <1.0 1 BHT (ppm) d <1.0 1 Aerobic plate count (CFU/g) 50 1 Coliform (MPN/g) 3.0 ...

  50. TOX-85: Toxicity Study of Tetrabromobisphenol A-bis(2,3-dibromopropyl... 2.7MB

    https://ntp.niehs.nih.gov/go/tox085

    ... (ppm) c 21.3 ± 3.08 16.8-23.7 4 Nitrite nitrogen (ppm) c 2.50 ± 1.56 0.30-3.86 4 BHA (ppm) d <1.0 - 4 BHT (ppm) d <1.0 - 4 Aerobic plate count (CFU/g) 10 ± 0.0 10 4 ...

 
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