-
TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf
... Noinformation was presented regarding exposure levels or the content o f contaminating minerals of the talc used. In another study, the role o f exposure t o talcum powder, tobac- ...
-
RoC Background Document: Silica, Crystalline (Respirable Size... 1.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/silica_no_app_508.pdf
... primarily of clay Foam in furniture and on rug backings Contain talc and silica Talcum powder Contains talc Paint Contains clay, talc, sand, and diatomite Unwashed root ...
-
CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
... preparations 27 7 9 43 Colognes/toilet waters 5 35 56 96 Perfumes 1 7 20 28 Powders dusting/talcum, aftershave talc 1 8 1 10 Sachets 10 14 4 28 Other fragrance preparations 1 4 ...
-
Minutes: BSC RoC; Dec. 13-15, 2000 205KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/minutes20001213.pdf
... Frederick wondered whether all the studies were done with non-fibous talc or whether some used fibrous. Dr. Kamel responded that before 1976, some samples of talcum powder were ...
-
TR-562: Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats... 6.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr562.pdf
TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF GOLDENSEAL ROOT POWDER ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF GOLDENSEAL ROOT POWDER (HYDRASTIS CANADENSIS) IN ...
-
Background Document: RoC: Cobalt-Tungsten Carbide: Powders and... 1.9MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/hardmetalsbd20100408_508.pdf
Report on Carcinogens Background Document for Cobalt-Tungsten Carbide: Powders and Hard ... Document for Cobalt-Tungsten Carbide: Powders and Hard Metals 3/16/09 i FOREWORD The ...
-
Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel... 6.5MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_panelreportparta_508.pdf
A - Peer Review of the Draft Background Document on Cobalt-Tungsten Carbide Powders and Hard Metals The Report on Carcinogens (RoC) expert panel for cobalt-tungsten carbide powders ...
-
Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel... 700KB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_panelreportpartb_508.pdf
Carbide Powders and Hard Metals and Scientific Justification for the Recommendation The Report on Carcinogens (RoC) expert panel for cobalt-tungsten carbide powders and hard ...
-
Abstract for TR-562 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr562
Toxicology and Carcinogenesis Studies of Goldenseal Root Powder in F344/N Rats and B6C3F1 ... Full Report PDF Abstract Goldenseal root powder is used in folk medicine for the treatment ...
-
Abstract for TER98007 62KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter98007
Developmental Toxicity Evaluation for Goldenseal Root Powder (Hydrastis Canadensis) ... Goldenseal (Hydrastis canadensis) root powder is readily available in OTC dietary ...
-
Abstract for TR-421 71KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr421
CASRN: 14807-96-6 Chemical Formula: Mg3Si10 (OH)2 Molecular Weight: 379.26 Synonyms/Common Names: Talcum; agalite; emtal 596; non-asbestiform talc; non-fibrous talc; steatite; ...
-
Abstract for TER99004 62KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter99004
Developmental Toxicity Evaluation for Goldenseal (Hydrastis Canadensis) Root Powder ... Goldenseal (Hydrastis canadensis) root powder is readily available in OTC dietary ...
-
Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten... 60KB
https://ntp.niehs.nih.gov/events/past/2000s/2008/panel_2008-12-09
Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten Carbide Powders and Hard ... Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten Carbide Powders and Hard ...
-
Agenda: RoC Cobalt-Tungsten Carbide Powders and Hard Metals Expert... 111KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_agenda20081210.pdf
Report on Carcinogens (RoC) Cobal t-Tungsten Carbide Powders and Hard Metal s Expert Panel ... Bernard North, Kennametal, Inc. . Dr. Kate Heim - Global Tungsten Powders . Mr. Bob Caron, ...
-
Abstract for TR-427 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr427
Turmeric oleoresin is the organic extract of turmeric, a ground powder from the root of ... are used in food items and curry powders, and there was little information on ...
-
Roster: RoC Cobalt-Tungsten Carbide Powders and Hard Metals Expert... 120KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_roster20081210.pdf
Report on Carcinogens (RoC) Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel Roster December 9 th -10 th , 2008 Max Costa, Ph.D., Chair Steven Markowitz, M.D. New York ...
-
Abstract for TR-410 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr410
Full Report PDF Abstract Naphthalene, a white, crystalline powder, is used as a moth repellent and in the manufacture of phthalic and anthranilic acids, naphthylamines, and ...
-
Abstract for TOX-80 65KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox080
Full Report PDF Abstract Sodium thioglycolate is a white powder with a melting point greater than 300°C. It appears as hygroscopic crystals with an unpleasant odor characteristic ...
-
Abstract for TR-512 76KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr512
Full Report PDF Abstract Elmiron®, a white powder, is the sodium salt of pentosan polysulfate, a semisynthetic sulfated polyanion composed of b-D-xylopyranose residues with ...
-
Abstract for TR-372 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr372
Full Report PDF Abstract 3,3'-Dimethoxybenzidine dihydrochloride is an off-white powder with a melting point of 274 degrees C. 3,3'-Dimethoxybenzidine is used principally as an ...
-
Abstract for TR-393 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr393
CASRN: 7681-49-4 Chemical Formula: NaF Molecular Weight: 41.99 Report Date: December 1990 Full Report PDF Abstract Sodium fluoride is a white, crystalline, water-soluble powder ...
-
Abstract for TR-432 69KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr432
Barium chloride dihydrate, a white crystalline granule or powder, is used in pigments, aluminum refining, leather tanning and coloring, the manufacture of magnesium metal, ...
-
Abstract for TR-240 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr240
Full Report PDF Abstract Propyl gallate is a white to nearly white odorless powder having a slightly bitter taste. Solutions of propyl gallate turn dark in the presence of iron or ...
-
Target Organs and Levels of Evidence for TR-562 58KB
https://ntp.niehs.nih.gov/data/tr/500s/tr562levels
Toxicology and Carcinogenesis Studies of Goldenseal Root Powder (CASRN GOLDENSEALRT) in ... Levels Study Laboratory Goldenseal root powder GOLDENSEALRT 02/25/2009 Dosed-Feed R&M: ...
-
Minutes: BSC TRRS; Feb. 25, 2009 76KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/minutes_final0209.pdf
......... 1 Goldenseal Root Powder ......Goldenseal Root Powder Dr. June Dunnick, NIEHS, introduced the studies of goldenseal root ...
-
Minutes: BSC; June 21-22, 2010 364KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2010/june/minutes20100622.pdf
Carcinogens: Cobalt- Tungsten Carbide: Powders and Hard Metals ......CoWC cobalt-tungsten carbide: powders and hard metals DERT Division of ...
-
NTP Response to BSC Peer Review Comments on the Draft Substances... 324KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2011/response062110bsc2011.pdf
Members 3 Cobalt-Tungsten Carbide: Powders and Hard Metals 4 BSC Comments and NTP ... cobalt-tungsten carbide: powders and hard metals, formaldehyde, and glass wool fibers. ...
-
Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
... Two cobalt-containing substances, 'cobalt sulfate' and 'cobalt-tungsten carbide: powders ... Cobalt-tungsten carbide: powders and hard metals, which was first listed in 2011 based on ...
-
Minutes: BSC; April 17-18, 2014 253KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/april/minutes20140418_508.pdf
6 IX. Draft RoC Concept: Goldenseal Root Powder ......IX. Draft RoC Concept: Goldenseal Root Powder A. Presentation Diane Spencer briefed the ...
-
Response to Expert Panels' Peer-Review Comments on Background... 354KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2011/responseexpertpanelreport2011.pdf
7 References 8 Cobalt-Tungsten Carbide: Powders and Hard Metals 9 Expert Panel Meeting 9 ... Cobalt-Tungsten Carbide: Hard Metals and Powders 9 Cobalt-Tungsten Carbide: Powders and ...
-
Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf
... Two cobalt-containing substances, 'cobalt sulfate' and 'cobalt-tungsten carbide: powders ... Cobalt-tungsten carbide: powders and hard metals, which was first listed in 2011 based on ...
-
Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf
... NTP 2014b (rats): Cobalt metal/powder; Inhalation ...... D-4 Table D-1b. NTP 2014b (mice): Cobalt metal/powder; Inhalation ...
-
Public Comment: Ruth Danzeisen of Cobalt Development Institute... 1.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/cdi20150708.pdf
... (and by extension Co dichloride, Co dinitrate and Co acetate), and Co metal powder. ... of the relevant fluid. hile Co metal powder is poorly soluble in water at 2 C, it is ...
-
Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf
... NTP 2014b (rats): Cobalt metal/powder; Inhalation ...... D-4 Table D-1b. NTP 2014b (mice): Cobalt metal/powder; Inhalation ...
-
Research Concept: Cobalt; 2014 690KB
https://ntp.niehs.nih.gov/ntp/roc/concept_docs/2014/cobalt_508.pdf
Two cobalt compounds, 'cobalt sulfate' and 'cobalt-tungsten carbide: powders and hard ... The greatest exposure occurs in industries using cemented tungsten-carbide, cobalt powder, ...
-
Botanical Dietary Supplements 78KB
https://ntp.niehs.nih.gov/whatwestudy/topics/botanical
Gum Guggul Extract Goldenseal root powder Ginkgo biloba extract Ginseng Kava kava ... Tablets Capsules Softgels Gelcaps Liquids Powders Echinacea, green tea extract, garlic, ...
-
RoC Background Document: Metallic Nickel and Certain Nickel Alloys... 1.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/ni_no_appendices_508.pdf
... injection of metallic nickel powder ......alloy, Raney nickel gray black powder or cubic crystals Insoluble in water and ethanol. ...
-
Comment: Antimony Trioxide (Attachment); Caroline Braibant, Geert... 9.7MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/braibant_attach2.pdf
... name: dioxodistiboxane Description: white powder Annex I index number: 051-005-00-X ... EC no.: 215-175-0 > 98.0 - <100 % (w/w) Powder, Particle size 0.2- 44µm Table 3. ...
-
Abstract for TR-54 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr054
by the munitions industry as a modifier for smokeless powders and, to a limited extent, as a gelatinizing and waterproofing agent in military and commercial explosive compositions. ...
-
Historical Controls: Pathology Tables by Feed for Mice 100KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_feed_path_hist09.pdf
729 50 (1) 43(715) 48.3 Goldenseal root powder Southern Research Institute 059201306 02/... 732 50 (5) 44(718) 51.9 Goldenseal root powder Southern Research Institute 059201306 02/...
-
Historical Controls: Pathology Tables by Oral/Feed for Fischer... 101KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_feed_path_hist09.pdf
729 50 (3) 33(679) 460.9 Goldenseal root powder Southern Research Institute 059201305 01/... 731 50 (5) 30(699) 326.0 Goldenseal root powder Southern Research Institute 059201305 01/...
-
RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
... Two cobalt-containing substances, cobalt sulfate' and cobalt-tungsten carbide: powders and ... Cobalt-tungsten carbide: powders and hard metals, which was first listed in 2011 based on ...
-
Background Document: RoC: Aristolochic Acids ; 2010 2.7MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/aristolochic_acids_final_508.pdf
... The weight-loss clinics had changed the weight-loss regimen to include powders from ... A follow-up investigation analyzed 46 batches of powders that were labeled as Stephania ...
-
Historical Controls: Pathology Tables by Oral/Feed for B6C3F1... 153KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/oralfeedmice2010mar.pdf
729 50(1) 43(715) 48.3 Goldenseal root powder Southern Research Institute 052000804 03/... 732 50(5) 44(718) 51.9 Goldenseal root powder Southern Research Institute 052000804 03/...
-
Historical Controls: Pathology Tables by Oral/Feed for Fischer... 154KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/oralfeedrats2010mar.pdf
729 50(3) 33(679) 460.9 Goldenseal root powder Southern Research Institute 052000803 03/... 731 50(5) 30(699) 326.0 Goldenseal root powder Southern Research Institute 052000803 03/...
-
TR-427: Turmeric Oleoresin (CASRN 8024-37-1) (Major Component... 16.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr427.pdf
... the organic extractof turmeric, a ground powder from the root o f the Curcuma plant, and ... are used in food items and curry powders, andthere was little information on their ...
-
RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf
... powder. It is soluble in acid, ammonium nitrate, and hot sulfuric acid and insoluble in cold and hot water. Cadmium carbonate occurs as a white amorphous powder that is ...
-
RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
... (199 4H 2 0; (CH 3 COz)2Ni mass or powder (soluble in 6 dilute ethanol water of ... Emerald 2.6 green cubic crystals, green powder Colorless -19.3 43 1.318 (17 volatile oq ...
-
RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf
... 10141-05-6 CoN 2 O 6 c 182.9 c red powder or crystals c 2.49 c 67.0 d 96/100 d ... Dermal contact with cemented carbide (i.e., hard-metal) powders and cobalt salts can ...
-
RoC Profile: Nickel Compounds and Metallic Nickel; 15th RoC 2021 170KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nickel.pdf
... In both rats and hamsters, metallic nickel powder caused tumors when ad- ministered by ... Intratracheal instillation of metallic nickel powder primarily caused adenocarcinoma, ...